Oxygen Availability for Porphyrin Biosynthesis Enzymes Determines the Production of Protoporphyrin IX (PpIX) during Hypoxia.

by Shimpei Otsuka, Kentaro Matsumoto, Motowo Nakajima, Tohru Tanaka, Shun-Ichiro Ogura
Published 2015-01-01

5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages

by Yuta Sugiyama, Yukari Hiraiwa, Yuichiro Hagiya, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura
Published 2018-12-01

The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation

by Kohei Yamashita, Yuichiro Hagiya, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka, Shun-ichiro Ogura
Published 2014-01-01

The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation.

by Mai Miura, Kensuke Ito, Maiko Hayashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura
Published 2015-01-01

Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA)

by Peter R. Rehani, Hanaa Iftikhar, Motowo Nakajima, Tohru Tanaka, Zaid Jabbar, Riyadh N. Rehani
Published 2019-01-01

Effects of 5-aminolevulinic acid supplementation on home-based walking training achievement in middle-aged depressive women: randomized, double-blind, crossover pilot study

by Hiroshi Suzuki, Shizue Masuki, Akiyo Morikawa, Yu Ogawa, Yoshi-ichiro Kamijo, Kiwamu Takahashi, Motowo Nakajima, Hiroshi Nose
Published 2018-05-01

The effect of iron ion on the specificity of photodynamic therapy with 5-aminolevulinic acid.

by Maiko Hayashi, Hideo Fukuhara, Keiji Inoue, Taro Shuin, Yuichiro Hagiya, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura
Published 2015-01-01

5‐ALA/SFC enhances HO‐1 expression through the MAPK/Nrf2 antioxidant pathway and attenuates murine tubular epithelial cell apoptosis

by Chi Liu, Masayuki Fujino, Shuoji Zhu, Yoshitaka Isaka, Hidenori Ito, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Ping Zhu, Xiao‐Kang Li
Published 2019-11-01

5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice.

by Shinichi Saitoh, Satoshi Okano, Hidekazu Nohara, Hiroshi Nakano, Nobuyuki Shirasawa, Akira Naito, Masayuki Yamamoto, Vincent P Kelly, Kiwamu Takahashi, Tohru Tanaka, Motowo Nakajima, Osamu Nakajima
Published 2018-01-01

The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain

by Feryal Al-Saber, Waleed Aldosari, Mariam Alselaiti, Hesham Khalfan, Ahmed Kaladari, Ghulam Khan, George Harb, Riyadh Rehani, Sizuka Kudo, Aya Koda, Tohru Tanaka, Motowo Nakajima, Abdulla Darwish
Published 2016-01-01

Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid

by Chikako Fujii, Kazutoshi Miyashita, Masanori Mitsuishi, Masaaki Sato, Kentaro Fujii, Hiroyuki Inoue, Aika Hagiwara, Sho Endo, Asuka Uto, Masaki Ryuzaki, Motowo Nakajima, Tohru Tanaka, Masanori Tamaki, Ayako Muraki, Toshihide Kawai, Hiroshi Itoh
Published 2017-06-01

Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.

by Huifang Hao, Yutaka Maeda, Takuya Fukazawa, Tomoki Yamatsuji, Munenori Takaoka, Xiao-Hong Bao, Junji Matsuoka, Tatsuo Okui, Tsuyoshi Shimo, Nagio Takigawa, Yasuko Tomono, Motowo Nakajima, Iris M Fink-Baldauf, Sandra Nelson, William Seibel, Ruben Papoian, Jeffrey A Whitsett, Yoshio Naomoto
Published 2013-01-01