Molecular modelling insights into a physiologically favourable approach to eicosanoid biosynthesis inhibition through novel thieno[2,3-b]pyridine derivatives

by Mosaad S. Mohamed, Yara E. Mansour, Hatem K. Amin, Moustafa E. El-Araby
Published 2018-01-01

Molecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on Paclitaxel.

by Moustafa E El-Araby, Abdelsattar M Omar, Maan T Khayat, Hanan A Assiri, Ahmed M Al-Abd
Published 2017-01-01

An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling

by Abdelsattar M. Omar, Osheiza Abdulmalik, Mohini S. Ghatge, Yosra A. Muhammad, Steven D. Paredes, Moustafa E. El-Araby, Martin K. Safo
Published 2020-11-01

New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase

by Fatmah A. S. Alasmary, Fatima S. Alnahdi, Abir Ben Bacha, Amr M. El-Araby, Nadine Moubayed, Ahmed M. Alafeefy, Moustafa E. El-Araby
Published 2017-01-01

Synthetic bulky NS4A peptide variants bind to and inhibit HCV NS3 protease

by Moustafa E. El-Araby, Abdelsattar M. Omar, Sameh H. Soror, Stefan T. Arold, Maan T. Khayat, Hani Z. Asfour, Faida Bamane, Mahmoud A. Elfaky
Published 2020-07-01

Bioassay Guided Isolation and Docking Studies of a Potential β-Lactamase Inhibitor from <i>Clutia myricoides</i>

by Mahmoud A. Elfaky, Ali M. El-Halawany, Abdulrahman E. Koshak, Khalid Z. Alshali, Moustafa E. El-Araby, Maan T. Khayat, Hossam M. Abdallah
Published 2020-05-01

1<i>H</i>-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease

by Abdelsattar M. Omar, Mahmoud A. Elfaky, Stefan T. Arold, Sameh H. Soror, Maan T. Khayat, Hani Z. Asfour, Faida H. Bamane, Moustafa E. El-Araby
Published 2020-03-01

Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin

by Abdelsattar M. Omar, Mona A. Mahran, Mohini S. Ghatge, Faida H. A. Bamane, Mostafa H. Ahmed, Moustafa E. El-Araby, Osheiza Abdulmalik, Martin K. Safo
Published 2016-08-01

Improving the Solubility and Oral Bioavailability of a Novel Aromatic Aldehyde Antisickling Agent (PP10) for the Treatment of Sickle Cell Disease

by Tarek A. Ahmed, Khalid M. El-Say, Fathy I. Abd-Allah, Abdelsattar M. Omar, Moustafa E. El-Araby, Yosra A. Muhammad, Piyusha P. Pagare, Yan Zhang, Khadijah A. Mohmmad, Osheiza Abdulmalik, Martin K. Safo
Published 2021-07-01