Molecular characterization of neuroprotective activities of plant based products could revive their utilization and lead discovery of new drug candidates for brain diseases

by Muralidhar L Hegde
Published 2014-01-01

A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis

by Joy Mitra, Muralidhar L Hegde
Published 2019-10-01

New Mechanisms of DNA Repair Defects in Fused in Sarcoma–Associated Neurodegeneration: Stage Set for DNA Repair-Based Therapeutics?

by Haibo Wang, Muralidhar L Hegde
Published 2019-06-01

Altered Mitochondrial Dynamics in Motor Neuron Disease: An Emerging Perspective

by Manohar Kodavati, Haibo Wang, Muralidhar L. Hegde
Published 2020-04-01

Loss of endosomal recycling factor RAB11 coupled with complex regulation of MAPK/ERK/AKT signaling in postmortem spinal cord specimens of sporadic amyotrophic lateral sclerosis pat...

by Joy Mitra, Pavana M. Hegde, Muralidhar L. Hegde
Published 2019-06-01

Pre-Replicative Repair of Oxidized Bases Maintains Fidelity in Mammalian Genomes: The Cowcatcher Role of NEIL1 DNA Glycosylase

by Suganya Rangaswamy, Arvind Pandey, Sankar Mitra, Muralidhar L. Hegde
Published 2017-06-01

Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis

by Johant Lakey-Beitia, Jagadeesh Kumar D., Muralidhar L. Hegde, K.S. Rao
Published 2019-11-01

Human DNA Glycosylase NEIL1’s Interactions with Downstream Repair Proteins Is Critical for Efficient Repair of Oxidized DNA Base Damage and Enhanced Cell Survival

by Istvan Boldogh, Sankar Mitra, Dutta Arijit, Pavana M. Hegde, Muralidhar L. Hegde
Published 2012-11-01

New evidence on α-synuclein and Tau binding to conformation and sequence specific GCFNx01 rich DNA: Relevance to neurological disorders

by P Vasudevaraju, Erika Guerrero, Muralidhar L Hegde, T B Collen, Gabrielle B Britton, K S Rao
Published 2012-01-01

RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease

by Haibo Wang, Suganya Rangaswamy, Manohar Kodavati, Joy Mitra, Wenting Guo, Erika N. Guerrero, Ludo Van Den Bosch, Muralidhar L. Hegde
Published 2019-12-01

New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases

by Joy Mitra, Erika N. Guerrero, Pavana M. Hegde, Haibo Wang, Istvan Boldogh, Kosagi Sharaf Rao, Sankar Mitra, Muralidhar L. Hegde
Published 2014-07-01

The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation

by Xueqing Ba, Leopoldo Aguilera-Aguirre, Qura Tul Ain Nmi Rashid, Attila Bacsi, Zsolt Radak, Sanjiv Sur, Koa Hosoki, Muralidhar L. Hegde, Istvan Boldogh
Published 2014-09-01

Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis

by Haibo Wang, Wenting Guo, Joy Mitra, Pavana M. Hegde, Tijs Vandoorne, Bradley J. Eckelmann, Sankar Mitra, Alan E. Tomkinson, Ludo Van Den Bosch, Muralidhar L. Hegde
Published 2018-09-01

The Chemical Basis of Intracerebral Hemorrhage and Cell Toxicity With Contributions From Eryptosis and Ferroptosis

by Paul J. Derry, Anh Tran Tram Vo, Aswini Gnanansekaran, Joy Mitra, Anton V. Liopo, Muralidhar L. Hegde, Ah-Lim Tsai, James M. Tour, James M. Tour, James M. Tour, Thomas A. Kent, Thomas A. Kent, Thomas A. Kent
Published 2020-12-01

MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice

by Arun Gupta, Clayton R. Hunt, Muralidhar L. Hegde, Sharmistha Chakraborty, Durga Udayakumar, Nobuo Horikoshi, Mayank Singh, Deepti B. Ramnarain, Walter N. Hittelman, Sarita Namjoshi, Aroumougame Asaithamby, Tapas K. Hazra, Thomas Ludwig, Raj K. Pandita, Jessica K. Tyler, Tej K. Pandita
Published 2014-07-01

MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice

by Arun Gupta, Clayton R. Hunt, Muralidhar L. Hegde, Sharmistha Chakraborty, Durga Udayakumar, Nobuo Horikoshi, Mayank Singh, Deepti B. Ramnarain, Walter N. Hittelman, Sarita Namjoshi, Aroumougame Asaithamby, Tapas K. Hazra, Thomas Ludwig, Raj K. Pandita, Jessica K. Tyler, Tej K. Pandita
Published 2014-07-01

The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.

by Arpita Chatterjee, Saikat Saha, Anirban Chakraborty, Anabela Silva-Fernandes, Santi M Mandal, Andreia Neves-Carvalho, Yongping Liu, Raj K Pandita, Muralidhar L Hegde, Pavana M Hegde, Istvan Boldogh, Tetsuo Ashizawa, Arnulf H Koeppen, Tej K Pandita, Patricia Maciel, Partha S Sarkar, Tapas K Hazra
Published 2015-01-01