Growth differentiation factor 15 as a potential therapeutic for treating obesity

by Clarence Hale, Murielle M. Véniant
Published 2021-04-01

Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis

by Jiayan Guo, Hanbing Mei, Zhen Sheng, Qingyuan Meng, Murielle M. Véniant, Hong Yin
Published 2020-12-01

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.

by Murielle M Véniant, Clarence Hale, Joan Helmering, Michelle M Chen, Shanaka Stanislaus, Jim Busby, Steven Vonderfecht, Jing Xu, David J Lloyd
Published 2012-01-01

A volumetric method for quantifying atherosclerosis in mice by using microCT: comparison to en face.

by David J Lloyd, Joan Helmering, Stephen A Kaufman, James Turk, Matt Silva, Sergio Vasquez, David Weinstein, Brad Johnston, Clarence Hale, Murielle M Véniant
Published 2011-04-01

Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice

by Constance H. Zlot, Laura M. Flynn, Murielle M. Véniant, Edward Kim, Martin Raabe, Sally P.A. McCormick, Patricia Ambroziak, Leslie M. McEvoy, Stephen G. Young
Published 1999-01-01

The evolving systemic biomarker milieu in obese ZSF1 rat model of human cardiometabolic syndrome: Characterization of the model and cardioprotective effect of GDF15.

by Marina Stolina, Xin Luo, Denise Dwyer, Chun-Ya Han, Rhonda Chen, Ying Zhang, YuMei Xiong, Yinhong Chen, Jun Yin, Artem Shkumatov, Brandon Ason, Clarence Hale, Murielle M Véniant
Published 2020-01-01

Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism

by Elizabeth A. Killion, Michelle Chen, James R. Falsey, Glenn Sivits, Todd Hager, Larissa Atangan, Joan Helmering, Jae Lee, Hongyan Li, Bin Wu, Yuan Cheng, Murielle M. Véniant, David J. Lloyd
Published 2020-10-01

Characterization of a novel glucokinase activator in rat and mouse models.

by Min Lu, Pingping Li, Gautam Bandyopadhyay, William Lagakos, Walter E Dewolf, Taylor Alford, Mark Joseph Chicarelli, Lance Williams, Deborah A Anderson, Brian R Baer, Maralee McVean, Marion Conn, Murielle M Véniant, Peter Coward
Published 2014-01-01

Identification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in mice[S]

by Todd Juan, Murielle M. Véniant, Joan Helmering, Philip Babij, Daniel M. Baker, Michael A. Damore, Michael B. Bass, Tibor Gyuris, Mark Chhoa, Chi-Ming Li, Chris Ebeling, Julie Amato, George A. Carlson, David J. Lloyd
Published 2009-03-01

FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein.

by Richard Smith, Amy Duguay, Alice Bakker, Peng Li, Jennifer Weiszmann, Melissa R Thomas, Benjamin M Alba, Xinle Wu, Jamila Gupte, Li Yang, Jennitte Stevens, Agnes Hamburger, Stephen Smith, Jiyun Chen, Renee Komorowski, Kevin W Moore, Murielle M Véniant, Yang Li
Published 2013-01-01

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

by Shu-Chen Lu, Michelle Chen, Larissa Atangan, Elizabeth A. Killion, Renee Komorowski, Yuan Cheng, Chawita Netirojjanakul, James R. Falsey, Marina Stolina, Denise Dwyer, Clarence Hale, Shanaka Stanislaus, Todd Hager, Veena A. Thomas, John M. Harrold, David J. Lloyd, Murielle M. Véniant
Published 2021-05-01

Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes.

by Randy Hecht, Yue-Sheng Li, Jeonghoon Sun, Ed Belouski, Michael Hall, Todd Hager, Junming Yie, Wei Wang, Dwight Winters, Stephen Smith, Chris Spahr, Lei-Ting Tam, Zhongnan Shen, Shanaka Stanislaus, Narumol Chinookoswong, Yvonne Lau, Allen Sickmier, Mark Leo Michaels, Thomas Boone, Murielle M Véniant, Jing Xu
Published 2012-01-01

Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia.

by Hongfei Ge, Jonitha Gardner, Xiaosu Wu, Ingrid Rulifson, Jinghong Wang, Yumei Xiong, Jingjing Ye, Edward Belouski, Ping Cao, Jie Tang, Ki Jeong Lee, Suzanne Coberly, Xinle Wu, Jamila Gupte, Lynn Miao, Li Yang, Natalie Nguyen, Bei Shan, Wen-Chen Yeh, Murielle M Véniant, Yang Li, Helene Baribault
Published 2015-01-01