Impaired B cell anergy is not sufficient to breach tolerance to nuclear antigen in Vκ8/3H9 lupus-prone mice.

by Kieran P Manion, Yuriy Baglaenko, Nan-Hua Chang, Nafiseh Talaei, Joan E Wither
Published 2020-01-01

IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice.

by Yuriy Baglaenko, Kieran P Manion, Nan-Hua Chang, Eric Gracey, Christina Loh, Joan E Wither
Published 2016-01-01

Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice.

by Nan-Hua Chang, Kieran P Manion, Christina Loh, Evelyn Pau, Yuriy Baglaenko, Joan E Wither
Published 2017-01-01

B cell activating factor (BAFF) and T cells cooperate to breach B cell tolerance in lupus-prone New Zealand Black (NZB) mice.

by Nan-Hua Chang, Yui-Ho Cheung, Christina Loh, Evelyn Pau, Valerie Roy, Yong-Chun Cai, Joan Wither
Published 2010-07-01

The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic diseas...

by Yuriy Baglaenko, Nan-Hua Chang, Sindhu R. Johnson, Waleed Hafiz, Kieran Manion, Dario Ferri, Babak Noamani, Dennisse Bonilla, Sina Rusta-Sellehy, Larissa Lisnevskaia, Earl Silverman, Arthur Bookman, Carolina Landolt-Marticorena, Joan Wither
Published 2018-11-01

Identification of a neutrophil-related gene expression signature that is enriched in adult systemic lupus erythematosus patients with active nephritis: Clinical/pathologic associat...

by Joan E Wither, Stephenie D Prokopec, Babak Noamani, Nan-Hua Chang, Dennisse Bonilla, Zahi Touma, Carmen Avila-Casado, Heather N Reich, James Scholey, Paul R Fortin, Paul C Boutros, Carolina Landolt-Marticorena
Published 2018-01-01