Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models

by Julian Biau, Julian Biau, Julian Biau, Julian Biau, Julian Biau, Julian Biau, Emmanuel Chautard, Emmanuel Chautard, Nathalie Berthault, Nathalie Berthault, Nathalie Berthault, Nathalie Berthault, Leanne de Koning, Leanne de Koning, Frank Court, Bruno Pereira, Pierre Verrelle, Pierre Verrelle, Pierre Verrelle, Pierre Verrelle, Marie Dutreix, Marie Dutreix, Marie Dutreix, Marie Dutreix
Published 2019-06-01

Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response.

by Maria Quanz, Danielle Chassoux, Nathalie Berthault, Céline Agrario, Jian-Sheng Sun, Marie Dutreix
Published 2009-07-01

DNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulation.

by Ewa Kotula, Wolfgang Faigle, Nathalie Berthault, Florent Dingli, Damarys Loew, Jian-Sheng Sun, Marie Dutreix, Maria Quanz
Published 2013-01-01

Evolution of tumor cells during AsiDNA treatment results in energy exhaustion, decrease in responsiveness to signal, and higher sensitivity to the drug

by Pierre‐Marie Girard, Nathalie Berthault, Maria Kozlac, Sofia Ferreira, Wael Jdey, Srividya Bhaskara, Sergey Alekseev, Frederic Thomas, Marie Dutreix
Published 2020-08-01

Preclinical Studies Comparing Efficacy and Toxicity of DNA Repair Inhibitors, Olaparib, and AsiDNA, in the Treatment of Carboplatin-Resistant Tumors

by Nirmitha I. Herath, Nirmitha I. Herath, Nirmitha I. Herath, Nirmitha I. Herath, Nathalie Berthault, Nathalie Berthault, Sylvain Thierry, Sylvain Thierry, Wael Jdey, Wael Jdey, Wael Jdey, Wael Jdey, Marie-Christine Lienafa, Marie-Christine Lienafa, Françoise Bono, Patricia Noguiez-Hellin, Jian-Sheng Sun, Marie Dutreix, Marie Dutreix
Published 2019-11-01