Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D

by Melissa Herwig, Melissa Herwig, Melissa Herwig, Melissa Herwig, Detmar Kolijn, Detmar Kolijn, Detmar Kolijn, Detmar Kolijn, Mária Lódi, Mária Lódi, Mária Lódi, Mária Lódi, Mária Lódi, Soraya Hölper, Árpád Kovács, Árpád Kovács, Árpád Kovács, Zoltán Papp, Kornelia Jaquet, Kornelia Jaquet, Kornelia Jaquet, Peter Haldenwang, Cris Dos Remedios, Peter H. Reusch, Andreas Mügge, Andreas Mügge, Marcus Krüger, Marcus Krüger, Jens Fielitz, Jens Fielitz, Wolfgang A. Linke, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani
Published 2020-04-01

Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator

by Detmar Kolijn, Detmar Kolijn, Detmar Kolijn, Detmar Kolijn, Árpád Kovács, Árpád Kovács, Árpád Kovács, Árpád Kovács, Melissa Herwig, Melissa Herwig, Melissa Herwig, Melissa Herwig, Mária Lódi, Mária Lódi, Mária Lódi, Mária Lódi, Mária Lódi, Marcel Sieme, Marcel Sieme, Abdulatif Alhaj, Abdulatif Alhaj, Abdulatif Alhaj, Peter Sandner, Zoltán Papp, Peter H. Reusch, Peter Haldenwang, Ines Falcão-Pires, Wolfgang A. Linke, Kornelia Jaquet, Kornelia Jaquet, Kornelia Jaquet, Sophie Van Linthout, Andreas Mügge, Andreas Mügge, Carsten Tschöpe, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani
Published 2020-05-01

Impact of Syndecan-2-Selected Mesenchymal Stromal Cells on the Early Onset of Diabetic Cardiomyopathy in Diabetic db/db Mice

by Kathleen Pappritz, Kathleen Pappritz, Kathleen Pappritz, Fengquan Dong, Kapka Miteva, Kapka Miteva, Arpad Kovacs, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Muhammad El-Shafeey, Bahtiyar Kerim, Lisa O'Flynn, Stephen Joseph Elliman, Timothy O'Brien, Nazha Hamdani, Nazha Hamdani, Nazha Hamdani, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Sophie Van Linthout, Sophie Van Linthout, Sophie Van Linthout
Published 2021-05-01

Stratified Treatment of Heart Failure with preserved Ejection Fraction: rationale and design of the STADIA‐HFpEF trial

by Mariëlle Scheffer, Annet Driessen‐Waaijer, Nazha Hamdani, Jochem W.D. Landzaat, Nini H. Jonkman, Walter J. Paulus, Loek vanHeerebeek
Published 2020-12-01

Integration of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G) into Cellular Structures

by Constanze Erdmann, Roua Hassoun, Sebastian Schmitt, Carlos Kikuti, Anne Houdusse, Antonina J. Mazur, Andreas Mügge, Nazha Hamdani, Matthias Geyer, Kornelia Jaquet, Hans Georg Mannherz
Published 2021-07-01

C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness

by Konstanze Michel, Melissa Herwig, Franziska Werner, Katarina Špiranec Spes, Marco Abeßer, Kai Schuh, Swati Dabral, Andreas Mügge, Hideo A. Baba, Boris V. Skryabin, Nazha Hamdani, Michaela Kuhn
Published 2020-11-01

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes

by Judith Krysiak, Andreas Unger, Lisa Beckendorf, Nazha Hamdani, Marion von Frieling-Salewsky, Margaret M. Redfield, Cris G. dos Remedios, Farah Sheikh, Ulrich Gergs, Peter Boknik, Wolfgang A. Linke
Published 2018-01-01

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.

by Irene Müller, Kathleen Pappritz, Konstantinos Savvatis, Kerstin Puhl, Fengquan Dong, Muhammad El-Shafeey, Nazha Hamdani, Isabell Hamann, Michel Noutsias, Carmen Infante-Duarte, Wolfgang A Linke, Sophie Van Linthout, Carsten Tschöpe
Published 2017-01-01

Prophylactic, single-drug cardioprotection in a comparative, experimental study of doxorubicin-induced cardiomyopathy

by Mária Lódi, Viktor Bánhegyi, Beáta Bódi, Alexandra Gyöngyösi, Árpád Kovács, Anita Árokszállási, Nazha Hamdani, Miklós Fagyas, István Édes, Zoltán Csanádi, István Czuriga, Zoltán Kisvárday, István Lekli, Péter Bai, Attila Tóth, Zoltán Papp, Dániel Czuriga
Published 2020-12-01

Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart

by Árpád Kovács, Melissa Herwig, Heidi Budde, Simin Delalat, Detmar Kolijn, Beáta Bódi, Roua Hassoun, Melina Tangos, Saltanat Zhazykbayeva, Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S. Dhalla, Andreas Mügge, Attila Tóth, Zoltán Papp, Judit Barta, Nazha Hamdani
Published 2021-06-01

The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts

by Heidi Budde, Roua Hassoun, Melina Tangos, Saltanat Zhazykbayeva, Melissa Herwig, Marharyta Varatnitskaya, Marcel Sieme, Simin Delalat, Innas Sultana, Detmar Kolijn, Kamilla Gömöri, Muhammad Jarkas, Mária Lódi, Kornelia Jaquet, Árpád Kovács, Hans Georg Mannherz, Vasco Sequeira, Andreas Mügge, Lars I. Leichert, Samuel Sossalla, Nazha Hamdani
Published 2021-07-01

De Novo Missense Mutations in <i>TNNC1</i> and <i>TNNI3</i> Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targetin...

by Roua Hassoun, Heidi Budde, Hans Georg Mannherz, Mária Lódi, Setsuko Fujita-Becker, Kai Thorsten Laser, Anna Gärtner, Karin Klingel, Desirée Möhner, Robert Stehle, Innas Sultana, Thomas Schaaf, Mario Majchrzak, Verena Krause, Christian Herrmann, Marc M. Nowaczyk, Andreas Mügge, Gabriele Pfitzer, Rasmus R. Schröder, Nazha Hamdani, Hendrik Milting, Kornelia Jaquet, Diana Cimiotti
Published 2021-09-01

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

by D. Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen, Chao-Chung Kuo, Ivan G. Costa, Christoph Schürmann, Matthias S. Leisegang, Ralf P. Brandes, Tijna Alekseeva, Boris Brill, Astrid Wietelmann, Christopher N. Johnson, Alexander Spring-Connell, Manuel Kaulich, Stanislas Werfel, Stefan Engelhardt, Marc N. Hirt, Kaja Yorgan, Thomas Eschenhagen, Luisa Kirchhof, Patrick Hofmann, Nicolas Jaé, Ilka Wittig, Nazha Hamdani, Corinne Bischof, Jaya Krishnan, Riekelt H. Houtkooper, Stefanie Dimmeler, Reinier A. Boon
Published 2020-04-01