Impact of Heparanase and the Tumor Microenvironment on Cancer Metastasis and Angiogenesis: Basic Aspects and Clinical Applications

by Israel Vlodavsky, Michael Elkin, Neta Ilan
Published 2011-01-01

Heparanase Loosens E-Cadherin-Mediated Cell-Cell Contact via Activation of Src

by Victoria Cohen-Kaplan, Neta Ilan, Israel Vlodavsky
Published 2020-01-01

Heparanase interacts with resistin and augments its activity.

by Daniela Novick, Sara Barak, Neta Ilan, Israel Vlodavsky
Published 2014-01-01

Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels.

by Itay Shafat, Neta Ilan, Samih Zoabi, Israel Vlodavsky, Farid Nakhoul
Published 2011-02-01

Elucidating the Consequences of Heparan Sulfate Binding by Heparanase 2

by Miriam Gross-Cohen, Sari Feld, Gil Arvatz, Neta Ilan, Israel Vlodavsky
Published 2021-01-01

Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans.

by Flonia Levy-Adam, Sari Feld, Edith Suss-Toby, Israel Vlodavsky, Neta Ilan
Published 2008-06-01

Clinical Significance of Urine Heparanase in Bladder Cancer Progression

by Itay Shafat, Dov Pode, Tamar Peretz, Neta Ilan, Israel Vlodavsky, Nisman Benjamin
Published 2008-02-01

Heparanase Localization and Expression by Head and Neck Cancer: Correlation with Tumor Progression and Patient Survival

by Ilana Doweck, Victoria Kaplan-Cohen, Inna Naroditsky, Edmond Sabo, Neta Ilan, Israel Vlodavsky
Published 2006-12-01

Heparanase Expression in Malignant Salivary Gl, Tumors Inversely Correlates with Long-Term Survival

by Ofer Ben-Izhak, Victoria Kaplan-Cohen, Neta Ilan, Shlomit Gan, Israel Vlodavsky, Rafael Nagler
Published 2006-10-01

A Pro-Tumorigenic Effect of Heparanase 2 (Hpa2) in Thyroid Carcinoma Involves Its Localization to the Nuclear Membrane

by Itai Margulis, Inna Naroditsky, Miriam Gross-Cohen, Neta Ilan, Israel Vlodavsky, Ilana Doweck, Ilana Doweck
Published 2021-04-01

Heparanase Levels Are Elevated in the Plasma of Pediatric Cancer Patients and Correlate with Response to Anticancer Treatment

by Itay Shafat, Ayelet Ben Barak, Sergey Postovsky, Ronit Elhasid, Neta Ilan, Israel Vlodavsky, Miriam Weyl Ben Arush
Published 2007-11-01

Elevated urine heparanase levels are associated with proteinuria and decreased renal allograft function.

by Itay Shafat, Amir Agbaria, Mona Boaz, Doron Schwartz, Ronny Baruch, Richard Nakash, Neta Ilan, Israel Vlodavsky, Talia Weinstein
Published 2012-01-01

Role of heparanase 2 (Hpa2) in gastric cancer

by Jingjing Liu, Ibrahim Knani, Miriam Gross-Cohen, Jiaxi Hu, Sumin Wang, Li Tang, Neta Ilan, Shiming Yang, Israel Vlodavsky
Published 2021-09-01

Nephroprotective effect of heparanase in experimental nephrotic syndrome.

by Suheir Assady, Joel Alter, Elena Axelman, Yaniv Zohar, Edmond Sabo, Michael Litvak, Marielle Kaplan, Neta Ilan, Israel Vlodavsky, Zaid Abassi
Published 2015-01-01

Clinical significance of heparanase splice variant (t5) in renal cell carcinoma: evaluation by a novel t5-specific monoclonal antibody.

by Uri Barash, Gil Arvatz, Roy Farfara, Inna Naroditsky, Ilana Doweck, Sari Feld, Ofer Ben-Izhak, Neta Ilan, Ofer Nativ, Israel Vlodavsky
Published 2012-01-01

The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression

by Preeti Singh, Alexandra Blatt, Sari Feld, Yaniv Zohar, Esraa Saadi, Liza Barki-Harrington, Edward Hammond, Neta Ilan, Israel Vlodavsky, Yehuda Chowers, Elizabeth Half
Published 2017-03-01

Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds

by Chakrabhavi Dhananjaya Mohan, Swetha Hari, Habbanakuppe D. Preetham, Shobith Rangappa, Uri Barash, Neta Ilan, S. Chandra Nayak, Vijai K. Gupta, Basappa, Israel Vlodavsky, Kanchugarakoppal S. Rangappa
Published 2019-05-01

The Role of Heparanase in the Pathogenesis of Acute Pancreatitis: A Potential Therapeutic Target

by Iyad Khamaysi, Preeti Singh, Susan Nasser, Hoda Awad, Yehuda Chowers, Edmond Sabo, Edward Hammond, Ian Gralnek, Irena Minkov, Alessandro Noseda, Neta Ilan, Israel Vlodavsky, Zaid Abassi
Published 2017-04-01

Macrophage-Induced Lymphangiogenesis and Metastasis following Paclitaxel Chemotherapy Is Regulated by VEGFR3

by Dror Alishekevitz, Svetlana Gingis-Velitski, Orit Kaidar-Person, Lilach Gutter-Kapon, Sandra D. Scherer, Ziv Raviv, Emmanuelle Merquiol, Yael Ben-Nun, Valeria Miller, Chen Rachman-Tzemah, Michael Timaner, Yelena Mumblat, Neta Ilan, David Loven, Dov Hershkovitz, Ronit Satchi-Fainaro, Galia Blum, Jonathan P. Sleeman, Israel Vlodavsky, Yuval Shaked
Published 2016-10-01