Development of Orally Active Thrombin Inhibitors for the Treatment of Thrombotic Disorder Diseases

by Li-Wei He, Wei-Chen Dai, Nian-Guang Li
Published 2015-06-01

Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives

by Pengxuan Zhang, Yuping Tang, Nian-Guang Li, Yue Zhu, Jin-Ao Duan
Published 2014-10-01

An efficient partial synthesis of 4′-O-methylquercetin via regioselective protection and alkylation of quercetin

by Nian-Guang Li, Zhi-Hao Shi, Yu-Ping Tang, Jian-Ping Yang, Jin-Ao Duan
Published 2009-11-01

Highly Efficient Esterification of Ferulic Acid Under Microwave Irradiation

by Bao-Quan Li, Jin-Ao Duan, Yu-Ping Tang, Nian-Guang Li, Zhi-Hao Shi
Published 2009-06-01

Synthesis and Protective Effect of Scutellarein on Focal Cerebral Ischemia/Reperfusion in Rats

by Nian-Guang Li, Qianping Shi, Yifan Fu, Li Zhang, Yuping Tang, Hao Tang, Minzhe Shen, Lihua Qian
Published 2012-09-01

An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin

by Ze-Xi Dong, Nian-Guang Li, Peng-Xuan Zhang, Ting Gu, Wen-Yu Wu, Zhi-Hao Shi
Published 2016-02-01

Development and Structural Modification of BACE1 Inhibitors

by Ting Gu, Wen-Yu Wu, Ze-Xi Dong, Shao-Peng Yu, Ying Sun, Yue Zhong, Yu-Ting Lu, Nian-Guang Li
Published 2016-12-01

Discovery of novel inhibitors disrupting HIF-1α/von Hippel–Lindau interaction through shape-based screening and cascade docking

by Xin Xue, Ning-Yi Zhao, Hai-Tao Yu, Yuan Sun, Chen Kang, Qiong-Bin Huang, Hao-Peng Sun, Xiao-Long Wang, Nian-Guang Li
Published 2016-12-01

Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer’s disease

by Wen-Yu Wu, Yu-Chen Dai, Nian-Guang Li, Ze-Xi Dong, Ting Gu, Zhi-Hao Shi, Xin Xue, Yu-Ping Tang, Jin-Ao Duan
Published 2017-01-01

Studies on the Protective Effects of Scutellarein against Neuronal Injury by Ischemia through the Analysis of Endogenous Amino Acids and Ca2+ Concentration Together with Ca2+-ATPas...

by Hao Tang, Ze-Xi Dong, Ting Gu, Nian-Guang Li, Yu-Ping Tang, Qian-Ping Shi, Jian-Ming Guo, Peng-Xuan Zhang, Jin-Ao Duan
Published 2015-01-01

A novel and efficient synthesis of phenanthrene derivatives via palladium/norbornadiene-catalyzed domino one-pot reaction

by Yue Zhong, Wen-Yu Wu, Shao-Peng Yu, Tian-Yuan Fan, Hai-Tao Yu, Nian-Guang Li, Zhi-Hao Shi, Yu-Ping Tang, Jin-Ao Duan
Published 2019-01-01

Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult.

by Hao Tang, Yuping Tang, Nian-Guang Li, Hang Lin, Weixia Li, Qianping Shi, Wei Zhang, Pengxuan Zhang, Zexi Dong, Minzhe Shen, Ting Gu, Jin-Ao Duan
Published 2015-01-01

Synthesis and Bio-Activity Evaluation of Scutellarein as a Potent Agent for the Therapy of Ischemic Cerebrovascular Disease

by An-Wei Ding, Jian-Ming Guo, Shu-Lin Song, Li Liu, Zhen-Jiang Wang, Hao Tang, Li Zhang, Yu-Ping Tang, Nian-Guang Li, Li-Hua Qian
Published 2011-11-01

Design, Synthesis, and In Vitro Antiplatelet Aggregation Activities of Ferulic Acid Derivatives

by Peng-Xuan Zhang, Hang Lin, Cheng Qu, Yu-Ping Tang, Nian-Guang Li, Jun Kai, Guanxiong Shang, Baoquan Li, Li Zhang, Hui Yan, Pei Liu, Jin-Ao Duan
Published 2015-01-01

A New and Efficient Synthesis of 6-O-Methylscutellarein, the Major Metabolite of the Natural Medicine Scutellarin

by Wei Zhang, Ze-Xi Dong, Ting Gu, Nian-Guang Li, Peng-Xuan Zhang, Wen-Yu Wu, Shao-Peng Yu, Yu-Ping Tang, Jian-Ping Yang, Zhi-Hao Shi
Published 2015-06-01

Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative

by Ting Gu, Yue Zhong, Yu-Ting Lu, Ying Sun, Ze-Xi Dong, Wen-Yu Wu, Zhi-Hao Shi, Nian-Guang Li, Xin Xue, Fang Fang, He-Min Li, Yu-Ping Tang
Published 2017-06-01

A Ferulic Acid Derivative FXS-3 Inhibits Proliferation and Metastasis of Human Lung Cancer A549 Cells via Positive JNK Signaling Pathway and Negative ERK/p38, AKT/mTOR and MEK/ERK...

by Shi-Jun Yue, Peng-Xuan Zhang, Yue Zhu, Nian-Guang Li, Yan-Yan Chen, Jia-Jia Li, Sai Zhang, Ru-Yi Jin, Hao Yan, Xu-Qin Shi, Yu-Ping Tang, Jin-Ao Duan
Published 2019-06-01

A New and Practical Synthetic Method for the Synthesis of 6-O-Methyl-scutellarein: One Metabolite of Scutellarin in Vivo

by Hang Lin, Wei Zhang, Ze-Xi Dong, Ting Gu, Nian-Guang Li, Zhi-Hao Shi, Jun Kai, Cheng Qu, Guan-Xiong Shang, Yu-Ping Tang, Fang Fang, He-Min Li, Jian-Ping Yang, Jin-Ao Duan
Published 2015-04-01