Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42

by Nicholas C. Zachos, Bharath Alamelumangpuram, Luke J. Lee, Peng Wang, Olga Kovbasnjuk
Published 2014-03-01

Recovery of Infectious Human Norovirus GII.4 Sydney From Fomites via Replication in Human Intestinal Enteroids

by Katie N. Overbey, Nicholas C. Zachos, Caroline Coulter, Joseph Jacangelo, Joseph Jacangelo, Kellogg J. Schwab
Published 2021-07-01

Regenerative Intestinal Stem Cells Induced by Acute and Chronic Injury: The Saving Grace of the Epithelium?

by William D. Rees, William D. Rees, Rene Tandun, Rene Tandun, Enoch Yau, Enoch Yau, Nicholas C. Zachos, Theodore S. Steiner, Theodore S. Steiner
Published 2020-11-01

Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors

by Sarah C. Pearce, Heidi G. Coia, Heidi G. Coia, J. P. Karl, Ida G. Pantoja-Feliciano, Nicholas C. Zachos, Kenneth Racicot
Published 2018-11-01

Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

by Julie G. In, Jianyi Yin, Roger Atanga, Michele Doucet, Robert N. Cole, Lauren DeVine, Mark Donowitz, Nicholas C. Zachos, Sarah E. Blutt, Mary K. Estes, Olga Kovbasnjuk
Published 2020-10-01

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived ColonoidsSummary

by Julie In, Jennifer Foulke-Abel, Nicholas C. Zachos, Anne-Marie Hansen, James B. Kaper, Harris D. Bernstein, Marc Halushka, Sarah Blutt, Mary K. Estes, Mark Donowitz, Olga Kovbasnjuk
Published 2016-01-01

Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

by Nesrin M. Hasan, Kelli F. Johnson, Jianyi Yin, Nicholas W. Baetz, Lea Fayad, Vadim Sherman, Sarah E. Blutt, Mary K. Estes, Vivek Kumbhari, Nicholas C. Zachos, Olga Kovbasnjuk
Published 2021-02-01

Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers

by C. Ming Tse, Julie G. In, Jianyi Yin, Mark Donowitz, Michele Doucet, Jennifer Foulke-Abel, Fernando Ruiz-Perez, James P. Nataro, Nicholas C. Zachos, James B. Kaper, Olga Kovbasnjuk
Published 2018-09-01