Truncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the A90V sequence...

by Heike J Wobst, Louise Delsing, Nicholas J Brandon, Stephen J Moss
Published 2017-01-01

Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes

by Joshua L. Smalley, Georgina Kontou, Georgina Kontou, Catherine Choi, Qiu Ren, David Albrecht, David Albrecht, Krithika Abiraman, Krithika Abiraman, Miguel A. Rodriguez Santos, Christopher E. Bope, Tarek Z. Deeb, Tarek Z. Deeb, Paul A. Davies, Nicholas J. Brandon, Nicholas J. Brandon, Stephen J. Moss, Stephen J. Moss
Published 2020-10-01

Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function

by Yvonne E. Moore, Leslie C. Conway, Heike J. Wobst, Nicholas J. Brandon, Tarek Z. Deeb, Stephen J. Moss, Stephen J. Moss, Stephen J. Moss
Published 2019-07-01

Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy

by Matt R. Kelley, Ross A. Cardarelli, Joshua L. Smalley, Thomas A. Ollerhead, Peter M. Andrew, Nicholas J. Brandon, Tarek Z. Deeb, Stephen J. Moss
Published 2018-06-01

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells.

by Jayashree Chadchankar, Victoria Korboukh, Leslie C Conway, Heike J Wobst, Chandler A Walker, Peter Doig, Steve J Jacobsen, Nicholas J Brandon, Stephen J Moss, Qi Wang
Published 2019-01-01

Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons

by M. Catarina Silva, Ghata A. Nandi, Sharon Tentarelli, Ian K. Gurrell, Tanguy Jamier, Diane Lucente, Bradford C. Dickerson, Dean G. Brown, Nicholas J. Brandon, Stephen J. Haggarty
Published 2020-06-01

Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods

by Carrie Wright, Anandita Rajpurohit, Emily E. Burke, Courtney Williams, Leonardo Collado-Torres, Martha Kimos, Nicholas J. Brandon, Alan J. Cross, Andrew E. Jaffe, Daniel R. Weinberger, Joo Heon Shin
Published 2019-06-01

Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin

by Rochelle M. Hines, Hans Michael Maric, Dustin J. Hines, Amit Modgil, Patrizia Panzanelli, Yasuko Nakamura, Anna J. Nathanson, Alan Cross, Tarek Deeb, Nicholas J. Brandon, Paul Davies, Jean-Marc Fritschy, Hermann Schindelin, Stephen J. Moss
Published 2018-08-01

Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures

by Anna J. Nathanson, Yihui Zhang, Joshua L. Smalley, Thomas A. Ollerhead, Miguel A. Rodriguez Santos, Peter M. Andrews, Heike J. Wobst, Yvonne E. Moore, Nicholas J. Brandon, Rochelle M. Hines, Paul A. Davies, Stephen J. Moss
Published 2019-07-01

Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway

by Jianjia Fan, Rui Qi Zhao, Cameron Parro, Wenchen Zhao, Hsien-Ya Chou, Jerome Robert, Tarek Z. Deeb, Carina Raynoschek, Samantha Barichievy, Ola Engkvist, Marcello Maresca, Ryan Hicks, Johan Meuller, Stephen J. Moss, Nicholas J. Brandon, Michael W. Wood, Iva Kulic, Cheryl L. Wellington
Published 2018-01-01

Axl receptor tyrosine kinase is a regulator of apolipoprotein E

by Wenchen Zhao, Jianjia Fan, Iva Kulic, Cheryl Koh, Amanda Clark, Johan Meuller, Ola Engkvist, Samantha Barichievy, Carina Raynoschek, Ryan Hicks, Marcello Maresca, Qi Wang, Dean G. Brown, Alvin Lok, Cameron Parro, Jerome Robert, Hsien-Ya Chou, Andrea M. Zuhl, Michael W. Wood, Nicholas J. Brandon, Cheryl L. Wellington
Published 2020-05-01

Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

by Nicola Micali, Suel-Kee Kim, Marcelo Diaz-Bustamante, Genevieve Stein-O’Brien, Seungmae Seo, Joo-Heon Shin, Brian G. Rash, Shaojie Ma, Yanhong Wang, Nicolas A. Olivares, Jon I. Arellano, Kristen R. Maynard, Elana J. Fertig, Alan J. Cross, Roland W. Bürli, Nicholas J. Brandon, Daniel R. Weinberger, Joshua G. Chenoweth, Daniel J. Hoeppner, Nenad Sestan, Pasko Rakic, Carlo Colantuoni, Ronald D. McKay
Published 2020-05-01

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs

by Emily E. Burke, Joshua G. Chenoweth, Joo Heon Shin, Leonardo Collado-Torres, Suel-Kee Kim, Nicola Micali, Yanhong Wang, Carlo Colantuoni, Richard E. Straub, Daniel J. Hoeppner, Huei-Ying Chen, Alana Sellers, Kamel Shibbani, Gregory R. Hamersky, Marcelo Diaz Bustamante, BaDoi N. Phan, William S. Ulrich, Cristian Valencia, Amritha Jaishankar, Amanda J. Price, Anandita Rajpurohit, Stephen A. Semick, Roland W. Bürli, James C. Barrow, Daniel J. Hiler, Stephanie C. Page, Keri Martinowich, Thomas M. Hyde, Joel E. Kleinman, Karen F. Berman, Jose A. Apud, Alan J. Cross, Nicholas J. Brandon, Daniel R. Weinberger, Brady J. Maher, Ronald D. G. McKay, Andrew E. Jaffe
Published 2020-01-01