Computational modeling and experimental validation of the EPI-X4/CXCR4 complex allows rational design of small peptide antagonists

by Pandian Sokkar, Mirja Harms, Christina Stürzel, Andrea Gilg, Gönül Kizilsavas, Martina Raasholm, Nico Preising, Manfred Wagner, Frank Kirchhoff, Ludger Ständker, Gilbert Weidinger, Benjamin Mayer, Jan Münch, Elsa Sanchez-Garcia
Published 2021-09-01

Respiratory ß-2-Microglobulin exerts pH dependent antimicrobial activity

by Armin Holch, Richard Bauer, Lia-Raluca Olari, Armando A. Rodriguez, Ludger Ständker, Nico Preising, Merve Karacan, Sebastian Wiese, Paul Walther, Yasser B. Ruiz-Blanco, Elsa Sanchez-Garcia, Christian Schumann, Jan Münch, Barbara Spellerberg
Published 2020-01-01

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

by Mirja Harms, Monica M.W. Habib, Simona Nemska, Antonella Nicolò, Andrea Gilg, Nico Preising, Pandian Sokkar, Sara Carmignani, Martina Raasholm, Gilbert Weidinger, Gönül Kizilsavas, Manfred Wagner, Ludger Ständker, Ashraf H. Abadi, Hassan Jumaa, Frank Kirchhoff, Nelly Frossard, Elsa Sanchez-Garcia, Jan Münch
Published 2021-09-01

A Placenta Derived C-Terminal Fragment of β-Hemoglobin With Combined Antibacterial and Antiviral Activity

by Rüdiger Groß, Richard Bauer, Franziska Krüger, Elke Rücker-Braun, Lia-Raluca Olari, Ludger Ständker, Nico Preising, Armando A. Rodríguez, Armando A. Rodríguez, Carina Conzelmann, Fabian Gerbl, Daniel Sauter, Frank Kirchhoff, Benjamin Hagemann, Jasmina Gačanin, Jasmina Gačanin, Tanja Weil, Tanja Weil, Yasser B. Ruiz-Blanco, Elsa Sanchez-Garcia, Wolf-Georg Forssmann, Annette Mankertz, Sabine Santibanez, Steffen Stenger, Paul Walther, Sebastian Wiese, Barbara Spellerberg, Jan Münch, Jan Münch
Published 2020-04-01

Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

by Lukas Wettstein, Tatjana Weil, Carina Conzelmann, Janis A. Müller, Rüdiger Groß, Maximilian Hirschenberger, Alina Seidel, Susanne Klute, Fabian Zech, Caterina Prelli Bozzo, Nico Preising, Giorgio Fois, Robin Lochbaum, Philip Maximilian Knaff, Volker Mailänder, Ludger Ständker, Dietmar Rudolf Thal, Christian Schumann, Steffen Stenger, Alexander Kleger, Günter Lochnit, Benjamin Mayer, Yasser B. Ruiz-Blanco, Markus Hoffmann, Konstantin M. J. Sparrer, Stefan Pöhlmann, Elsa Sanchez-Garcia, Frank Kirchhoff, Manfred Frick, Jan Münch
Published 2021-03-01