A Comparative Study of Human and Zebrafish Pregnane X Receptor Activities of Pesticides and Steroids Using In Vitro Reporter Gene Assays

by Nicolas Creusot, Clémentine Garoche, Marina Grimaldi, Abdelhay Boulahtouf, Barbara Chiavarina, William Bourguet, Patrick Balaguer
Published 2021-05-01

Retrospective screening of high-resolution mass spectrometry archived digital samples can improve environmental risk assessment of emerging contaminants: A case study on antifungal...

by Nicolas Creusot, Carmen Casado-Martinez, Aurea Chiaia-Hernandez, Karin Kiefer, Benoit J.D. Ferrari, Qiuguo Fu, Nicole Munz, Christian Stamm, Ahmed Tlili, Juliane Hollender
Published 2020-06-01

The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor

by Nicolas Creusot, Matthieu Gassiot, Elina Alaterre, Barbara Chiavarina, Marina Grimaldi, Abdelhay Boulahtouf, Lucia Toporova, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Alice Matheux, Roger Rahmani, Céline Gongora, Alexandre Evrard, Philippe Pourquier, Patrick Balaguer
Published 2020-07-01