Three different approaches to C-H bond functionalization in the synthesis of antitumor alkaloids rhazinilam, rhazinal and rhazinicine

by Delphine Le Floc’h, Nicolas Gouault, Michèle David, Pierre van de Weghe
Published 2010-07-01

Total synthesis of (−)-epimyrtine by a gold-catalyzed hydroamination approach

by Thi Thanh Huyen Trinh, Khanh Hung Nguyen, Patricia de Aguiar Amaral, Nicolas Gouault
Published 2013-10-01

FLUOROUS SUPPORTED SYNTHESIS OF PYRAZOLONE DERIVATIVES FROM ALLYLIC ALCOHOLS USING A PALLADIUM-CATALYZED STRATEGY

by Nicolas Gouault, Alexandre Cariou, Jean-François Cupif, Patrícia de Aguiar Amaral, Michèle David

Isolation and Structure Identification of Novel Brominated Diketopiperazines from Nocardia ignorata—A Lichen-Associated Actinobacterium

by Alba Noël, Solenn Ferron, Isabelle Rouaud, Nicolas Gouault, Jean-Pierre Hurvois, Sophie Tomasi
Published 2017-02-01

Combined approaches for drug design points the way to novel proline racemase inhibitor candidates to fight Chagas' disease.

by Armand Berneman, Lory Montout, Sophie Goyard, Nathalie Chamond, Alain Cosson, Simon d'Archivio, Nicolas Gouault, Philippe Uriac, Arnaud Blondel, Paola Minoprio
Published 2013-01-01

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.

by Patricia de Aguiar Amaral, Delphine Autheman, Guilherme Dias de Melo, Nicolas Gouault, Jean-François Cupif, Sophie Goyard, Patricia Dutra, Nicolas Coatnoan, Alain Cosson, Damien Monet, Frederick Saul, Ahmed Haouz, Philippe Uriac, Arnaud Blondel, Paola Minoprio
Published 2018-10-01