Hyaluronan Inhibits Tlr-4-Dependent RANKL Expression in Human Rheumatoid Arthritis Synovial Fibroblasts.

by Tatsuo Watanabe, Nobunori Takahashi, Shinya Hirabara, Naoki Ishiguro, Toshihisa Kojima
Published 2016-01-01

Hyaluronan Oligosaccharides Induce MMP-1 and -3 via Transcriptional Activation of NF-κB and p38 MAPK in Rheumatoid Synovial Fibroblasts.

by Masahiro Hanabayashi, Nobunori Takahashi, Yasumori Sobue, Shinya Hirabara, Naoki Ishiguro, Toshihisa Kojima
Published 2016-01-01

Hyaluronan promotes TRPV4-induced chondrogenesis in ATDC5 cells.

by Yoshikazu Ogawa, Nobunori Takahashi, Toki Takemoto, Tsuyoshi Nishiume, Mochihito Suzuki, Naoki Ishiguro, Toshihisa Kojima
Published 2019-01-01

Two cases of autoimmune pulmonary alveolar proteinosis with rheumatoid arthritis

by Satoru Ito, Keiko Wakahara, Toshihisa Kojima, Nobunori Takahashi, Kimitoshi Nishiwaki, Etsuro Yamaguchi, Yoshinori Hasegawa
Published 2017-07-01

Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis

by Yoshifumi Ohashi, Nobunori Takahashi, Kenya Terabe, Saho Tsuchiya, Toshihisa Kojima, Cheryl B. Knudson, Warren Knudson, Shiro Imagama
Published 2021-07-01

Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway

by Kyosuke Hattori, Nobunori Takahashi, Kenya Terabe, Yoshifumi Ohashi, Kenji Kishimoto, Yutaka Yokota, Mochihito Suzuki, Toshihisa Kojima, Shiro Imagama
Published 2021-07-01

Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors

by Shuichi Okamoto, Nobuaki Suzuki, Atsuo Suzuki, Sachiko Suzuki, Shogo Tamura, Mochihito Suzuki, Nobunori Takahashi, Toshihisa Kojima, Takeshi Kanematsu, Tetsuhito Kojima, Hitoshi Kiyoi, Naoki Ishiguro, Tadashi Matsushita
Published 2019-10-01

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis

by Yuhsuke Ohmi, Wataru Ise, Akira Harazono, Daisuke Takakura, Hidehiro Fukuyama, Yoshihiro Baba, Masashi Narazaki, Hirofumi Shoda, Nobunori Takahashi, Yuki Ohkawa, Shuting Ji, Fumihiro Sugiyama, Keishi Fujio, Atsushi Kumanogoh, Kazuhiko Yamamoto, Nana Kawasaki, Tomohiro Kurosaki, Yoshimasa Takahashi, Koichi Furukawa
Published 2016-04-01

Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry

by Nobunori Takahashi, Shuji Asai, Tomonori Kobayakawa, Atsushi Kaneko, Tatsuo Watanabe, Takefumi Kato, Tsuyoshi Nishiume, Hisato Ishikawa, Yutaka Yoshioka, Yasuhide Kanayama, Tsuyoshi Watanabe, Yuji Hirano, Masahiro Hanabayashi, Yuichiro Yabe, Yutaka Yokota, Mochihito Suzuki, Yasumori Sobue, Kenya Terabe, Naoki Ishiguro, Toshihisa Kojima
Published 2020-12-01