Machine Learning-Enhanced T Cell Neoepitope Discovery for Immunotherapy Design

by Joana Martins, Carlos Magalhães, Miguel Rocha, Nuno S Osório
Published 2019-05-01

Evolutionary Genetics of <i>Mycobacterium tuberculosis</i> and HIV-1: “The Tortoise and the Hare”

by Ana Santos-Pereira, Carlos Magalhães, Pedro M. M. Araújo, Nuno S. Osório
Published 2021-01-01

The Troika Host–Pathogen–Extrinsic Factors in Tuberculosis: Modulating Inflammation and Clinical Outcomes

by Helder Novais Bastos, Helder Novais Bastos, Helder Novais Bastos, Nuno S. Osório, Nuno S. Osório, Sebastien Gagneux, Sebastien Gagneux, Iñaki Comas, Iñaki Comas, Margarida Saraiva, Margarida Saraiva
Published 2018-01-01

Characterization of a large cluster of HIV-1 A1 infections detected in Portugal and connected to several Western European countries

by Pedro M. M. Araújo, Alexandre Carvalho, Marta Pingarilho, BEST-HOPE study group, Ana B. Abecasis, Nuno S. Osório
Published 2019-05-01

Nationwide Study of Drug Resistance Mutations in HIV-1 Infected Individuals under Antiretroviral Therapy in Brazil

by Ana Santos-Pereira, Vera Triunfante, Pedro M. M. Araújo, Joana Martins, Helena Soares, Eva Poveda, Bernardino Souto, Nuno S. Osório
Published 2021-05-01

Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis.

by Carolina Ferreira, Inês Mesquita, Ana Margarida Barbosa, Nuno Sampaio Osório, Egídio Torrado, Charles-Joly Beauparlant, Arnaud Droit, Cristina Cunha, Agostinho Carvalho, Bhaskar Saha, Jerôme Estaquier, Ricardo Silvestre
Published 2020-03-01

Heterogeneous Streptomycin Resistance Level Among Mycobacterium tuberculosis Strains From the Same Transmission Cluster

by Deisy M. G. C. Rocha, Deisy M. G. C. Rocha, Deisy M. G. C. Rocha, Deisy M. G. C. Rocha, Carlos Magalhães, Carlos Magalhães, Baltazar Cá, Baltazar Cá, Angelica Ramos, Teresa Carvalho, Iñaki Comas, Iñaki Comas, João Tiago Guimarães, João Tiago Guimarães, João Tiago Guimarães, Helder Novais Bastos, Helder Novais Bastos, Helder Novais Bastos, Margarida Saraiva, Margarida Saraiva, Nuno S. Osório, Nuno S. Osório
Published 2021-06-01

Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response.

by Jenny Carmona, Andrea Cruz, Lucia Moreira-Teixeira, Carole Sousa, Jeremy Sousa, Nuno S Osorio, Ana L Saraiva, Stefan Svenson, Gunilla Kallenius, Jorge Pedrosa, Fernando Rodrigues, Antonio G Castro, Margarida Saraiva
Published 2013-01-01

The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation.

by Agostinho Carvalho, Nuno S Osório, Margarida Saraiva, Cristina Cunha, Agostinho J Almeida, Maria Teixeira-Coelho, Paula Ludovico, Jorge Pedrosa, Lucia Pitzurra, Franco Aversa, Luigina Romani, António G Castro, Fernando Rodrigues
Published 2011-01-01

Characterizing HIV-1 Genetic Subtypes and Drug Resistance Mutations among Children, Adolescents and Pregnant Women in Sierra Leone

by George A. Yendewa, Sulaiman Lakoh, Sahr A. Yendewa, Khadijah Bangura, Andrés Tabernilla, Lucia Patiño, Darlinda F. Jiba, Alren O. Vandy, Samuel P. Massaquoi, Nuno S. Osório, Gibrilla F. Deen, Foday Sahr, Robert A. Salata, Eva Poveda
Published 2021-08-01

Correction: A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.

by Helder Novais Bastos, Nuno S Osório, António Gil Castro, Angélica Ramos, Teresa Carvalho, Leonor Meira, David Araújo, Leonor Almeida, Rita Boaventura, Patrícia Fragata, Catarina Chaves, Patrício Costa, Miguel Portela, Ivo Ferreira, Sara Pinto Magalhães, Fernando Rodrigues, Rui Sarmento Castro, Raquel Duarte, João Tiago Guimarães, Margarida Saraiva
Published 2020-01-01

A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.

by Helder Novais Bastos, Nuno S Osório, António Gil Castro, Angélica Ramos, Teresa Carvalho, Leonor Meira, David Araújo, Leonor Almeida, Rita Boaventura, Patrícia Fragata, Catarina Chaves, Patrício Costa, Miguel Portela, Ivo Ferreira, Sara Pinto Magalhães, Fernando Rodrigues, Rui Sarmento-Castro, Raquel Duarte, João Tiago Guimarães, Margarida Saraiva
Published 2016-01-01

Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes

by Richard Thomson-Luque, Lasse Votborg-Novél, Wanangwa Ndovie, Carolina M. Andrade, Moussa Niangaly, Charalampos Attipa, Nathalia F. Lima, Drissa Coulibaly, Didier Doumtabe, Bouréima Guindo, Bourama Tangara, Fayçal Maiga, Abdoulaye Kassoum Kone, Karim Traore, Kassoum Kayentao, Aissata Ongoiba, Safiatou Doumbo, Mahamadou A. Thera, Boubacar Traoré, Karl Seydel, Nuno S. Osório, Silvia Portugal
Published 2021-07-01

Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production

by Jeremy Sousa, Baltazar Cá, Ana Raquel Maceiras, Luisa Simões-Costa, Kaori L. Fonseca, Ana Isabel Fernandes, Angélica Ramos, Teresa Carvalho, Leandro Barros, Carlos Magalhães, Álvaro Chiner-Oms, Henrique Machado, Maria Isabel Veiga, Albel Singh, Rui Pereira, António Amorim, Jorge Vieira, Cristina P. Vieira, Apoorva Bhatt, Fernando Rodrigues, Pedro N. S. Rodrigues, Sebastien Gagneux, António Gil Castro, João Tiago Guimarães, Helder Novais Bastos, Nuno S. Osório, Iñaki Comas, Margarida Saraiva
Published 2020-04-01

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

by Samuel M. Gonçalves, Cláudio Duarte-Oliveira, Cláudia F. Campos, Vishukumar Aimanianda, Rob ter Horst, Luis Leite, Toine Mercier, Paulo Pereira, Miguel Fernández-García, Daniela Antunes, Cláudia S. Rodrigues, Catarina Barbosa-Matos, Joana Gaifem, Inês Mesquita, António Marques, Nuno S. Osório, Egídio Torrado, Fernando Rodrigues, Sandra Costa, Leo AB. Joosten, Katrien Lagrou, Johan Maertens, João F. Lacerda, António Campos, Gordon D. Brown, Axel A. Brakhage, Coral Barbas, Ricardo Silvestre, Frank L. van de Veerdonk, Georgios Chamilos, Mihai G. Netea, Jean-Paul Latgé, Cristina Cunha, Agostinho Carvalho
Published 2020-05-01