Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis

by Naiara Santana-Codina, Anjali A. Roeth, Yi Zhang, Annan Yang, Oksana Mashadova, John M. Asara, Xiaoxu Wang, Roderick T. Bronson, Costas A. Lyssiotis, Haoqiang Ying, Alec C. Kimmelman
Published 2018-11-01

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism

by Diana G. Wang, Marcia N. Paddock, Mark R. Lundquist, Janet Y. Sun, Oksana Mashadova, Solomon Amadiume, Timothy W. Bumpus, Cindy Hodakoski, Benjamin D. Hopkins, Matthew Fine, Amanda Hill, T. Jonathan Yang, Jeremy M. Baskin, Lukas E. Dow, Lewis C. Cantley
Published 2019-05-01

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

by Barbara S. Nelson, Lin Lin, Daniel M. Kremer, Cristovão M. Sousa, Cecilia Cotta-Ramusino, Amy Myers, Johanna Ramos, Tina Gao, Ilya Kovalenko, Kari Wilder-Romans, Joseph Dresser, Mary Davis, Ho-Joon Lee, Zeribe C. Nwosu, Scott Campit, Oksana Mashadova, Brandon N. Nicolay, Zachary P. Tolstyka, Christopher J. Halbrook, Sriram Chandrasekaran, John M. Asara, Howard C. Crawford, Lewis C. Cantley, Alec C. Kimmelman, Daniel R. Wahl, Costas A. Lyssiotis
Published 2020-01-01