Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1.

by Christian Löw, Caroline Jegerschöld, Michael Kovermann, Per Moberg, Pär Nordlund
Published 2012-01-01

Functional Properties and Molecular Architecture of Leukotriene A4 Hydrolase, a Pivotal Catalyst of Chemotactic Leukotriene Formation

by Jesper Z. Haeggström, Pär Nordlund, Marjolein M.G.M. Thunnissen
Published 2002-01-01

Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31.

by Esben M Quistgaard, Christian Löw, Per Moberg, Fatma Guettou, Karthik Maddi, Pär Nordlund
Published 2013-01-01

Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A.

by Rebecca Dovega, Susan Tsutakawa, Esben M Quistgaard, Madhanagopal Anandapadamanaban, Christian Löw, Pär Nordlund
Published 2014-01-01

Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine.

by Kelly Hew, Sue-Li Dahlroth, Saranya Veerappan, Lucy Xin Pan, Tobias Cornvik, Pär Nordlund
Published 2015-01-01

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.

by Lionel Trésaugues, Thomas Lundbäck, Martin Welin, Susanne Flodin, Tomas Nyman, Camilla Silvander, Susanne Gräslund, Pär Nordlund
Published 2015-01-01

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

by Louise Egeblad, Martin Welin, Susanne Flodin, Susanne Gräslund, Liya Wang, Jan Balzarini, Staffan Eriksson, Pär Nordlund
Published 2012-01-01

The crystal structure of the Dachshund domain of human SnoN reveals flexibility in the putative protein interaction surface.

by Tomas Nyman, Lionel Trésaugues, Martin Welin, Lari Lehtiö, Susanne Flodin, Camilla Persson, Ida Johansson, Martin Hammarström, Pär Nordlund
Published 2010-09-01

HF-EPR, Raman, UV/VIS light spectroscopic, and DFT studies of the ribonucleotide reductase R2 tyrosyl radical from Epstein-Barr virus.

by Ane B Tomter, Giorgio Zoppellaro, Florian Schmitzberger, Niels H Andersen, Anne-Laure Barra, Henrik Engman, Pär Nordlund, K Kristoffer Andersson
Published 2011-01-01

Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase

by Sing Mei Lim, Dan Chen, Hsiangling Teo, Annette Roos, Anna Elisabet Jansson, Tomas Nyman, Lionel Trésaugues, Konstantin Pervushin, Pär Nordlund
Published 2013-06-01

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

by Helena Almqvist, Hanna Axelsson, Rozbeh Jafari, Chen Dan, André Mateus, Martin Haraldsson, Andreas Larsson, Daniel Martinez Molina, Per Artursson, Thomas Lundbäck, Pär Nordlund
Published 2016-03-01

Nanobody mediated crystallization of an archeal mechanosensitive channel.

by Christian Löw, Yin Hoe Yau, Els Pardon, Caroline Jegerschöld, Lisa Wåhlin, Esben M Quistgaard, Per Moberg, Susana Geifman-Shochat, Jan Steyaert, Pär Nordlund
Published 2013-01-01

Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA

by Wendi Sun, Lingyun Dai, Han Yu, Brenda Puspita, Tianyun Zhao, Feng Li, Justin L. Tan, Yan Ting Lim, Ming Wei Chen, Radoslaw M. Sobota, Daniel G. Tenen, Nayana Prabhu, Pär Nordlund
Published 2019-06-01

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

by Sophia Ceder, Sofi E. Eriksson, Ying Yu Liang, Emarndeena H. Cheteh, Si Min Zhang, Kenji M. Fujihara, Julie Bianchi, Vladimir J. N. Bykov, Lars Abrahmsen, Nicholas J. Clemons, Pär Nordlund, Sean G. Rudd, Klas G. Wiman
Published 2021-07-01

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

by Yan Ting Lim, Nayana Prabhu, Lingyun Dai, Ka Diam Go, Dan Chen, Lekshmy Sreekumar, Louise Egeblad, Staffan Eriksson, Liyan Chen, Saranya Veerappan, Hsiang Ling Teo, Chris Soon Heng Tan, Johan Lengqvist, Andreas Larsson, Radoslaw M Sobota, Pär Nordlund
Published 2018-01-01

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality

by Mayumi Kitagawa, Pei-Ju Liao, Kyung Hee Lee, Jasmine Wong, See Cheng Shang, Noriaki Minami, Oltea Sampetrean, Hideyuki Saya, Dai Lingyun, Nayana Prabhu, Go Ka Diam, Radoslaw Sobota, Andreas Larsson, Pär Nordlund, Frank McCormick, Sujoy Ghosh, David M. Epstein, Brian W. Dymock, Sang Hyun Lee
Published 2017-12-01