Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E

by Geoffrey Masuyer, Jonathan R. Davies, Pål Stenmark
Published 2021-08-01

Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

by Jonathan R. Davies, Geoffrey Masuyer, Pål Stenmark
Published 2020-09-01

Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding

by Robert Gustafsson, Sicai Zhang, Geoffrey Masuyer, Min Dong, Pål Stenmark
Published 2018-04-01

Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion

by Jana Škerlová, Jens Berndtsson, Hendrik Nolte, Martin Ott, Pål Stenmark
Published 2021-09-01

Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction.

by Pål Stenmark, Jérôme Dupuy, Akihiro Imamura, Makoto Kiso, Raymond C Stevens
Published 2008-08-01

Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC

by Sicai Zhang, Ronnie P.-A. Berntsson, William H. Tepp, Liang Tao, Eric A. Johnson, Pål Stenmark, Min Dong
Published 2017-11-01

A neurotoxin that specifically targets Anopheles mosquitoes

by Estefania Contreras, Geoffrey Masuyer, Nadia Qureshi, Swati Chawla, Harpal S. Dhillon, Han Lim Lee, Jianwu Chen, Pål Stenmark, Sarjeet S. Gill
Published 2019-06-01

Identification and characterization of a novel botulinum neurotoxin

by Sicai Zhang, Geoffrey Masuyer, Jie Zhang, Yi Shen, Daniel Lundin, Linda Henriksson, Shin-Ichiro Miyashita, Markel Martínez-Carranza, Min Dong, Pål Stenmark
Published 2017-08-01

The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications

by Hansjörg Götzke, Markus Kilisch, Markel Martínez-Carranza, Shama Sograte-Idrissi, Abirami Rajavel, Thomas Schlichthaerle, Niklas Engels, Ralf Jungmann, Pål Stenmark, Felipe Opazo, Steffen Frey
Published 2019-09-01

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.

by Linxiang Yin, Geoffrey Masuyer, Sicai Zhang, Jie Zhang, Shin-Ichiro Miyashita, David Burgin, Laura Lovelock, Shu-Fen Coker, Tian-Min Fu, Pål Stenmark, Min Dong
Published 2020-03-01

Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors

by Liang Tao, Lisheng Peng, Ronnie P.-A. Berntsson, Sai Man Liu, SunHyun Park, Feifan Yu, Christopher Boone, Shilpa Palan, Matthew Beard, Pierre-Etienne Chabrier, Pål Stenmark, Johannes Krupp, Min Dong
Published 2017-07-01

NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir

by Rina Nishii, Takanori Mizuno, Daniel Rehling, Colton Smith, Brandi L. Clark, Xujie Zhao, Scott A. Brown, Brandon Smart, Takaya Moriyama, Yuji Yamada, Tatsuo Ichinohe, Makoto Onizuka, Yoshiko Atsuta, Lei Yang, Wenjian Yang, Paul G. Thomas, Pål Stenmark, Motohiro Kato, Jun J. Yang
Published 2021-07-01

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

by Brent D. G. Page, Nicholas C. K. Valerie, Roni H. G. Wright, Olov Wallner, Rebecka Isaksson, Megan Carter, Sean G. Rudd, Olga Loseva, Ann-Sofie Jemth, Ingrid Almlöf, Jofre Font-Mateu, Sabin Llona-Minguez, Pawel Baranczewski, Fredrik Jeppsson, Evert Homan, Helena Almqvist, Hanna Axelsson, Shruti Regmi, Anna-Lena Gustavsson, Thomas Lundbäck, Martin Scobie, Kia Strömberg, Pål Stenmark, Miguel Beato, Thomas Helleday
Published 2018-01-01

Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

by Brent D. G. Page, Nicholas C. K. Valerie, Roni H. G. Wright, Olov Wallner, Rebecka Isaksson, Megan Carter, Sean G. Rudd, Olga Loseva, Ann-Sofie Jemth, Ingrid Almlöf, Jofre Font-Mateu, Sabin Llona-Minguez, Pawel Baranczewski, Fredrik Jeppsson, Evert Homan, Helena Almqvist, Hanna Axelsson, Shruti Regmi, Anna-Lena Gustavsson, Thomas Lundbäck, Martin Scobie, Kia Strömberg, Pål Stenmark, Miguel Beato, Thomas Helleday
Published 2019-11-01

A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family

by Jordi Carreras-Puigvert, Marinka Zitnik, Ann-Sofie Jemth, Megan Carter, Judith E. Unterlass, Björn Hallström, Olga Loseva, Zhir Karem, José Manuel Calderón-Montaño, Cecilia Lindskog, Per-Henrik Edqvist, Damian J. Matuszewski, Hammou Ait Blal, Ronnie P. A. Berntsson, Maria Häggblad, Ulf Martens, Matthew Studham, Bo Lundgren, Carolina Wählby, Erik L. L. Sonnhammer, Emma Lundberg, Pål Stenmark, Blaz Zupan, Thomas Helleday
Published 2017-11-01