CD8 Co-Receptor Enhances T-Cell Activation without Any Effect on Initial Attachment

by Philippe Robert, Laurent Limozin, P. Anton van der Merwe, Pierre Bongrand
Published 2021-02-01

MHC binding affects the dynamics of different T-cell receptors in different ways.

by Bernhard Knapp, P Anton van der Merwe, Omer Dushek, Charlotte M Deane
Published 2019-09-01

Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity.

by Himadri Mukhopadhyay, Shaun-Paul Cordoba, Philip K Maini, P Anton van der Merwe, Omer Dushek
Published 2013-01-01

Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses.

by Nigel J Burroughs, Karsten Köhler, Vladimir Miloserdov, Michael L Dustin, P Anton van der Merwe, Daniel M Davis
Published 2011-08-01

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics

by Michael I Barton, Stuart A MacGowan, Mikhail A Kutuzov, Omer Dushek, Geoffrey John Barton, P Anton van der Merwe
Published 2021-08-01

A generic cell surface ligand system for studying cell-cell recognition.

by Eleanor M Denham, Michael I Barton, Susannah M Black, Marcus J Bridge, Ben de Wet, Rachel L Paterson, P Anton van der Merwe, Jesse Goyette
Published 2019-12-01

The discriminatory power of the T cell receptor

by Johannes Pettmann, Anna Huhn, Enas Abu Shah, Mikhail A Kutuzov, Daniel B Wilson, Michael L Dustin, Simon J Davis, P Anton van der Merwe, Omer Dushek
Published 2021-05-01