Chymase uptake by cardiomyocytes results in myosin degradation in cardiac volume overload

by Pamela C. Powell, Chih-Chang Wei, Lianwu Fu, Betty Pat, Wayne E. Bradley, James F. Collawn, Louis J. Dell'Italia
Published 2019-04-01

Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss.

by Chih-Chang Wei, Yuanwen Chen, Lindsay C Powell, Junying Zheng, Ke Shi, Wayne E Bradley, Pamela C Powell, Sarfaraz Ahmad, Carlos M Ferrario, Louis J Dell'Italia
Published 2012-01-01

Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog.

by Junying Zheng, Chih-Chang Wei, Naoki Hase, Ke Shi, Cheryl R Killingsworth, Silvio H Litovsky, Pamela C Powell, Tsunefumi Kobayashi, Carlos M Ferrario, Andras Rab, Inmaculada Aban, James F Collawn, Louis J Dell'Italia
Published 2014-01-01