Arabidopsis thaliana Article Bacillus thuringiensis Experimental evolution Pathogenesis Plant-microbe interaction Rho factor bacterial colonization bacterial strain bacterial virulence bacterium isolate carbohydrate carbohydrate metabolism cell differentiation cell lineage confocal laser scanning microscopy evolutionary adaptation gene mutation genetic transcription genomic DNA genotype phenotype correlation insect larva nonhuman nonsense mutation pathogenesis phenotype plant microorganism interaction plant root plant seed toxicity