Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues

by Tapan Kumar Mohanta, Nanaocha Sharma, Pietro Arina, Paola Defilippi
Published 2020-01-01

The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy

by Vincenzo Salemme, Giorgia Centonze, Federica Cavallo, Paola Defilippi, Laura Conti
Published 2021-03-01

p130Cas/BCAR1 and p140Cap/SRCIN1 Adaptors: The Yin Yang in Breast Cancer?

by Giorgia Centonze, Dora Natalini, Vincenzo Salemme, Andrea Costamagna, Sara Cabodi, Paola Defilippi
Published 2021-10-01

p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.

by Maria del Pilar Camacho Leal, Alessandra Pincini, Giusy Tornillo, Elisa Fiorito, Brigitte Bisaro, Elisa Di Luca, Emilia Turco, Paola Defilippi, Sara Cabodi
Published 2012-01-01

Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion

by Marianna Sciortino, Maria del Pilar Camacho-Leal, Francesca Orso, Elena Grassi, Andrea Costamagna, Paolo Provero, Wayne Tam, Emilia Turco, Paola Defilippi, Daniela Taverna, Sara Cabodi
Published 2017-04-01

Mapping of p140Cap phosphorylation sites: the EPLYA and EGLYA motifs have a key role in tyrosine phosphorylation and Csk binding, and are substrates of the Abl kinase.

by Daniele Repetto, Simona Aramu, Elisabetta Boeri Erba, Nanaocha Sharma, Silvia Grasso, Isabella Russo, Ole N Jensen, Sara Cabodi, Emilia Turco, Paola Di Stefano, Paola Defilippi
Published 2013-01-01

Correction to: Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation

by Maria del Pilar Camacho Leal, Andrea Costamagna, Beatrice Tassone, Stefania Saoncella, Matilde Simoni, Dora Natalini, Aurora Dadone, Marianna Sciortino, Emilia Turco, Paola Defilippi, Enzo Calautti, Sara Cabodi
Published 2018-11-01

Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation

by Maria del Pilar Camacho Leal, Andrea Costamagna, Beatrice Tassone, Stefania Saoncella, Matilde Simoni, Dora Natalini, Aurora Dadone, Marianna Sciortino, Emilia Turco, Paola Defilippi, Enzo Calautti, Sara Cabodi
Published 2018-11-01

Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

by Moitza Principe, Simone Borgoni, Mariafrancesca Cascione, Michelle Samuel Chattaragada, Sammy Ferri-Borgogno, Michela Capello, Sara Bulfamante, Jennifer Chapelle, Francesca Di Modugno, Paola Defilippi, Paola Nisticò, Paola Cappello, Chiara Riganti, Stefano Leporatti, Francesco Novelli
Published 2017-01-01

Dissecting the Shared and Context-Dependent Pathways Mediated by the p140Cap Adaptor Protein in Cancer and in Neurons

by Jennifer Chapelle, Oksana Sorokina, Colin McLean, Vincenzo Salemme, Annalisa Alfieri, Costanza Angelini, Alessandro Morellato, Annie Adrait, Elisabetta Menna, Elisabetta Menna, Michela Matteoli, Michela Matteoli, Yohann Couté, Ugo Ala, Emilia Turco, Paola Defilippi, J. Douglas Armstrong
Published 2019-10-01

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

by Tânia D. F. Costa, Ting Zhuang, Julie Lorent, Emilia Turco, Helene Olofsson, Miriam Masia-Balague, Miao Zhao, Parisa Rabieifar, Neil Robertson, Raoul Kuiper, Jonas Sjölund, Matthias Spiess, Pablo Hernández-Varas, Uta Rabenhorst, Pernilla Roswall, Ran Ma, Xiaowei Gong, Johan Hartman, Kristian Pietras, Peter D. Adams, Paola Defilippi, Staffan Strömblad
Published 2019-08-01

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

by Silvia Grasso, Jennifer Chapelle, Vincenzo Salemme, Simona Aramu, Isabella Russo, Nicoletta Vitale, Ludovica Verdun di Cantogno, Katiuscia Dallaglio, Isabella Castellano, Augusto Amici, Giorgia Centonze, Nanaocha Sharma, Serena Lunardi, Sara Cabodi, Federica Cavallo, Alessia Lamolinara, Lorenzo Stramucci, Enrico Moiso, Paolo Provero, Adriana Albini, Anna Sapino, Johan Staaf, Pier Paolo Di Fiore, Giovanni Bertalot, Salvatore Pece, Daniela Tosoni, Stefano Confalonieri, Manuela Iezzi, Paola Di Stefano, Emilia Turco, Paola Defilippi
Published 2017-03-01

Correction: Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries

by Silvia Grasso, Jennifer Chapelle, Vincenzo Salemme, Simona Aramu, Isabella Russo, Nicoletta Vitale, Ludovica Verdun di Cantogno, Katiuscia Dallaglio, Isabella Castellano, Augusto Amici, Giorgia Centonze, Nanaocha Sharma, Serena Lunardi, Sara Cabodi, Federica Cavallo, Alessia Lamolinara, Lorenzo Stramucci, Enrico Moiso, Paolo Provero, Adriana Albini, Anna Sapino, Johan Staaf, Pier Paolo Di Fiore, Giovanni Bertalot, Salvatore Pece, Daniela Tosoni, Stefano Confalonieri, Manuela Iezzi, Paola Di Stefano, Emilia Turco, Paola Defilippi
Published 2018-03-01

Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis

by Kevin Peikert, Enrica Federti, Alessandro Matte, Gabriela Constantin, Enrica Caterina Pietronigro, Paolo Francesco Fabene, Paola Defilippi, Emilia Turco, Federico Del Gallo, Pietro Pucci, Angela Amoresano, Anna Illiano, Flora Cozzolino, Maria Monti, Francesca Garello, Enzo Terreno, Seth Leo Alper, Hannes Glaß, Lisann Pelzl, Katja Akgün, Tjalf Ziemssen, Rainer Ordemann, Florian Lang, Anna Maria Brunati, Elena Tibaldi, Immacolata Andolfo, Achille Iolascon, Giuseppe Bertini, Mario Buffelli, Carlo Zancanaro, Erika Lorenzetto, Angela Siciliano, Massimiliano Bonifacio, Adrian Danek, Ruth Helen Walker, Andreas Hermann, Lucia De Franceschi
Published 2021-05-01

Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders

by Annalisa Alfieri, Oksana Sorokina, Annie Adrait, Annie Adrait, Annie Adrait, Costanza Angelini, Isabella Russo, Alessandro Morellato, Michela Matteoli, Michela Matteoli, Elisabetta Menna, Elisabetta Menna, Elisabetta Boeri Erba, Elisabetta Boeri Erba, Elisabetta Boeri Erba, Colin McLean, J. Douglas Armstrong, Ugo Ala, Ugo Ala, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Alfredo Brusco, Alfredo Brusco, Yohann Couté, Yohann Couté, Yohann Couté, Silvia De Rubeis, Silvia De Rubeis, Emilia Turco, Paola Defilippi
Published 2017-06-01