Folding circular permutants of IL-1β: route selection driven by functional frustration.

by Dominique T Capraro, Shachi Gosavi, Melinda Roy, José N Onuchic, Patricia A Jennings
Published 2012-01-01

Correction: Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation.

by Sulyman Barkho, Levi C T Pierce, Sheng Li, Joseph A Adams, Patricia A Jennings
Published 2015-01-01

Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation.

by Sulyman Barkho, Levi C T Pierce, Sheng Li, Joseph A Adams, Patricia A Jennings
Published 2015-01-01

Pierced Lasso Bundles are a new class of knot-like motifs.

by Ellinor Haglund, Joanna I Sulkowska, Jeffrey K Noel, Heiko Lammert, José N Onuchic, Patricia A Jennings
Published 2014-06-01

The unique cysteine knot regulates the pleotropic hormone leptin.

by Ellinor Haglund, Joanna I Sułkowska, Zhao He, Gen-Sheng Feng, Patricia A Jennings, José N Onuchic
Published 2012-01-01

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis.

by Colin H Lipper, Mark L Paddock, José N Onuchic, Ron Mittler, Rachel Nechushtai, Patricia A Jennings
Published 2015-01-01

Geometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State Ensemble.

by Kaitlin M Fisher, Ellinor Haglund, Jeffrey K Noel, Kendra L Hailey, José N Onuchic, Patricia A Jennings
Published 2015-01-01

Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase function.

by Michael A Jamros, Leandro C Oliveira, Paul C Whitford, José N Onuchic, Joseph A Adams, Patricia A Jennings
Published 2012-01-01

Designing bacterial signaling interactions with coevolutionary landscapes.

by Ryan R Cheng, Ellinor Haglund, Nicholas S Tiee, Faruck Morcos, Herbert Levine, Joseph A Adams, Patricia A Jennings, José N Onuchic
Published 2018-01-01

Distal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk).

by Sulyman Barkho, Levi C T Pierce, Maria L McGlone, Sheng Li, Virgil L Woods, Ross C Walker, Joseph A Adams, Patricia A Jennings
Published 2013-01-01

Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs.

by Sagi Tamir, John A Zuris, Lily Agranat, Colin H Lipper, Andrea R Conlan, Dorit Michaeli, Yael Harir, Mark L Paddock, Ron Mittler, Zvi Ioav Cabantchik, Patricia A Jennings, Rachel Nechushtai
Published 2013-01-01

Interactions between mitoNEET and NAF-1 in cells.

by Ola Karmi, Sarah H Holt, Luhua Song, Sagi Tamir, Yuting Luo, Fang Bai, Ammar Adenwalla, Merav Darash-Yahana, Yang-Sung Sohn, Patricia A Jennings, Rajeev K Azad, Jose' N Onuchic, Faruck Morcos, Rachel Nechushtai, Ron Mittler
Published 2017-01-01