Diabetes, Oxidative Stress, and DNA Damage Modulate Cranial Neural Crest Cell Development and the Phenotype Variability of Craniofacial Disorders

by Sharien Fitriasari, Paul A. Trainor, Paul A. Trainor
Published 2021-05-01

Making Headway: The Roles of Hox Genes and Neural Crest Cells in Craniofacial Development

by Paul A. Trainor
Published 2003-01-01

Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia.

by Kimberly E Inman, Patricia Purcell, Tsutomu Kume, Paul A Trainor
Published 2013-01-01

Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling.

by Hiroshi Kurosaka, Paul A Trainor, Margot Leroux-Berger, Angelo Iulianella
Published 2015-01-01

Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.

by Daisuke Sakai, Jill Dixon, Michael J Dixon, Paul A Trainor
Published 2012-01-01

Prevention of Treacher Collins syndrome craniofacial anomalies in mouse models via maternal antioxidant supplementation

by Daisuke Sakai, Jill Dixon, Annita Achilleos, Michael Dixon, Paul A. Trainor
Published 2016-01-01

The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development

by Soma Dash, Shachi Bhatt, Shachi Bhatt, Lisa L. Sandell, Christopher W. Seidel, Youngwook Ahn, Robb E. Krumlauf, Robb E. Krumlauf, Paul A. Trainor, Paul A. Trainor
Published 2020-10-01

Branchiomeric Muscle Development Requires Proper Retinoic Acid Signaling

by Qi Wang, Qi Wang, Qi Wang, Lin Xu, Jiro Miura, Mithun Kumar Saha, Yume Uemura, Lisa L. Sandell, Paul A. Trainor, Paul A. Trainor, Takashi Yamashiro, Hiroshi Kurosaka
Published 2021-07-01

Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate

by Qi Wang, Hiroshi Kurosaka, Masataka Kikuchi, Akihiro Nakaya, Paul A. Trainor, Takashi Yamashiro
Published 2019-10-01

RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis.

by Lisa L Sandell, Megan L Lynn, Kimberly E Inman, William McDowell, Paul A Trainor
Published 2012-01-01

The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome.

by Kristin E Noack Watt, Annita Achilleos, Cynthia L Neben, Amy E Merrill, Paul A Trainor
Published 2016-07-01

Antagonism between Retinoic Acid and Fibroblast Growth Factor Signaling during Limb Development

by Thomas J. Cunningham, Xianling Zhao, Lisa L. Sandell, Sylvia M. Evans, Paul A. Trainor, Gregg Duester
Published 2013-05-01

Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects.

by Jennifer F Dennis, Hiroshi Kurosaka, Angelo Iulianella, Jennifer Pace, Nancy Thomas, Sharon Beckham, Trevor Williams, Paul A Trainor
Published 2012-01-01

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis.

by Thomas J Cunningham, Thomas Brade, Lisa L Sandell, Mark Lewandoski, Paul A Trainor, Alexandre Colas, Mark Mercola, Gregg Duester
Published 2015-01-01

Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities

by Alexios A. Panoutsopoulos, Alexios A. Panoutsopoulos, Angelo Harlan De Crescenzo, Angelo Harlan De Crescenzo, Albert Lee, Albert Lee, Amelia MacKenzie Lu, Adam P. Ross, Adam P. Ross, Laura N. Borodinsky, Laura N. Borodinsky, Ralph Marcucio, Paul A. Trainor, Paul A. Trainor, Konstantinos S. Zarbalis, Konstantinos S. Zarbalis, Konstantinos S. Zarbalis
Published 2020-09-01

Transcriptional Elongation Factor Elongin A Regulates Retinoic Acid-Induced Gene Expression during Neuronal Differentiation

by Takashi Yasukawa, Shachi Bhatt, Tamotsu Takeuchi, Junya Kawauchi, Hidehisa Takahashi, Aya Tsutsui, Takuya Muraoka, Makoto Inoue, Masayuki Tsuda, Shigetaka Kitajima, Ronald C. Conaway, Joan W. Conaway, Paul A. Trainor, Teijiro Aso
Published 2012-11-01

Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.

by Patrick Callier, Pierre Calvel, Armine Matevossian, Periklis Makrythanasis, Pascal Bernard, Hiroshi Kurosaka, Anne Vannier, Christel Thauvin-Robinet, Christelle Borel, Séverine Mazaud-Guittot, Antoine Rolland, Christèle Desdoits-Lethimonier, Michel Guipponi, Céline Zimmermann, Isabelle Stévant, Françoise Kuhne, Béatrice Conne, Federico Santoni, Sandy Lambert, Frederic Huet, Francine Mugneret, Jadwiga Jaruzelska, Laurence Faivre, Dagmar Wilhelm, Bernard Jégou, Paul A Trainor, Marilyn D Resh, Stylianos E Antonarakis, Serge Nef
Published 2014-05-01