Genome Editing Human Pluripotent Stem Cells to Model β-Cell Disease and Unmask Novel Genetic Modifiers

by Matthew N. George, Karla F. Leavens, Karla F. Leavens, Karla F. Leavens, Paul Gadue, Paul Gadue
Published 2021-06-01

OCT4 Coordinates with WNT Signaling to Pre-pattern Chromatin at the SOX17 Locus during Human ES Cell Differentiation into Definitive Endoderm

by Lei Ying, Jason A. Mills, Deborah L. French, Paul Gadue
Published 2015-10-01

Factors Regulating Stem Cell Biology in Development and Disease

by Stefan Liebau, Paul Gadue, Kodandaramireddy Nalapareddy, Guido von Figura, Alexander Kleger
Published 2016-01-01

Generation of Hermansky Pudlak syndrome type 2 (HPS2) induced pluripotent stem cells (iPSCs)

by Jean Ann Maguire, Lin Lu, Jason A. Mills, Lisa M. Sullivan, Paul Gadue, Deborah L. French
Published 2016-03-01

Generation of human control iPS cell line CHOPWT10 from healthy adult peripheral blood mononuclear cells

by Jean Ann Maguire, Alyssa L. Gagne, Chintan D. Jobaliya, Shilpa Gandre-Babbe, Paul Gadue, Deborah L. French
Published 2016-03-01

Generation of Hermansky–Pudlak Syndrome Type 1 (HPS1) induced pluripotent stem cells (iPSCs)

by Jean Ann Maguire, Lin Lu, Jason A. Mills, Lisa M. Sullivan, Alyssa Gagne, Paul Gadue, Deborah L. French
Published 2016-03-01

Generation of human control iPSC line CHOPi004-A from juvenile foreskin fibroblast cells

by Somdutta Mukherjee, Alyssa L. Gagne, Jean Ann Maguire, Chintan D. Jobaliya, Jason A. Mills, Paul Gadue, Deborah L. French
Published 2020-12-01

Generation of poikiloderma with neutropenia (PN) induced pluripotent stem cells (iPSCs)

by Jason A. Mills, Kristin M. Hudock, Spencer K. Sullivan, Pamela Herrera, Lisa M. Sullivan, Paul Gadue, Deborah L. French
Published 2015-11-01

Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN...

by Jean Ann Maguire, Alyssa L. Gagne, Pedro Gonzalez-Alegre, Beverly L. Davidson, Vikram Shakkottai, Paul Gadue, Deborah L. French
Published 2019-01-01

Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets

by Karla F. Leavens, Chia-min Liao, Alyssa L. Gagne, Siddharth Kishore, Fabian L. Cardenas-Diaz, Deborah L. French, Paul Gadue
Published 2021-01-01

Tropomyosin 1 genetically constrains in vitro hematopoiesis

by Christopher Stephen Thom, Chintan D Jobaliya, Kimberly Lorenz, Jean Ann Maguire, Alyssa Gagne, Paul Gadue, Deborah L French, Benjamin Franklin Voight
Published 2020-05-01

Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL

by Alyssa L. Gagne, Jean Ann Maguire, Shilpa Gandre-Babbe, Stella T. Chou, Sarah K. Tasian, Mignon L. Loh, Mitchell J. Weiss, Paul Gadue, Deborah L. French
Published 2018-08-01

The negative impact of Wnt signaling on megakaryocyte and primitive erythroid progenitors derived from human embryonic stem cells

by Prasuna Paluru, Kristin M. Hudock, Xin Cheng, Jason A. Mills, Lei Ying, Aline M. Galvão, Lin Lu, Amita Tiyaboonchai, Xiuli Sim, Spencer K. Sullivan, Deborah L. French, Paul Gadue
Published 2014-03-01

GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells

by Amita Tiyaboonchai, Fabian L. Cardenas-Diaz, Lei Ying, Jean Ann Maguire, Xiuli Sim, Chintan Jobaliya, Alyssa L. Gagne, Siddharth Kishore, Diana E. Stanescu, Nkecha Hughes, Diva D. De Leon, Deborah L. French, Paul Gadue
Published 2017-03-01

Correction: AAV-Mediated Gene Therapy for Choroideremia: Preclinical Studies in Personalized Models.

by Vidyullatha Vasireddy, Jason A Mills, Rajashekhar Gaddameedi, Etiena Basner-Tschakarjan, Monika Kohnke, Aaron D Black, Krill Alexandrov, Shangzhen Zhou, Albert M Maguire, Daniel C Chung, Helen Mac, Lisa Sullivan, Paul Gadue, Jeannette L Bennicelli, Deborah L French, Jean Bennett
Published 2015-01-01

AAV-mediated gene therapy for choroideremia: preclinical studies in personalized models.

by Vidyullatha Vasireddy, Jason A Mills, Rajashekhar Gaddameedi, Etiena Basner-Tschakarjan, Monika Kohnke, Aaron D Black, Krill Alexandrov, Shangzhen Zhou, Albert M Maguire, Daniel C Chung, Helen Mac, Lisa Sullivan, Paul Gadue, Jeannette L Bennicelli, Deborah L French, Jean Bennett
Published 2013-01-01

Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells

by Andrew A. Wilson, Lei Ying, Marc Liesa, Charis-Patricia Segeritz, Jason A. Mills, Steven S. Shen, Jyhchang Jean, Geordie C. Lonza, Derek C. Liberti, Alex H. Lang, Jean Nazaire, Adam C. Gower, Franz-Josef Müeller, Pankaj Mehta, Adriana Ordóñez, David A. Lomas, Ludovic Vallier, George J. Murphy, Gustavo Mostoslavsky, Avrum Spira, Orian S. Shirihai, Maria I. Ramirez, Paul Gadue, Darrell N. Kotton
Published 2015-05-01