Can CRISPR help in the fight against parasitic worms?

by Paul McVeigh, Aaron G Maule
Published 2019-01-01

Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor.

by Mostafa Zamanian, Prince N Agbedanu, Nicolas J Wheeler, Paul McVeigh, Michael J Kimber, Tim A Day
Published 2012-01-01

FMRFamide-like peptides (FLPs) enhance voltage-gated calcium currents to elicit muscle contraction in the human parasite Schistosoma mansoni.

by Ekaterina Novozhilova, Michael J Kimber, Hai Qian, Paul McVeigh, Alan P Robertson, Mostafa Zamanian, Aaron G Maule, Tim A Day
Published 2010-08-01

Tissue-specific transcriptome analyses provide new insights into GPCR signalling in adult Schistosoma mansoni.

by Steffen Hahnel, Nic Wheeler, Zhigang Lu, Arporn Wangwiwatsin, Paul McVeigh, Aaron Maule, Matthew Berriman, Timothy Day, Paula Ribeiro, Christoph G Grevelding
Published 2018-01-01

Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes

by Paul McVeigh, Erin McCammick, Paul McCusker, Duncan Wells, Jane Hodgkinson, Steve Paterson, Angela Mousley, Nikki J. Marks, Aaron G. Maule
Published 2018-04-01

Uptake of macromolecules by cercariae during skin penetration and transformation to schistosomula (Schistosoma mansoni)

by Joyce Thornhill, John Kusel, Fabricia Alvisi de Oliviera, Fabio Ribeiro, Symone Fulgêncio Lima, Paulo Marcos Zech Coelho, Paul McVeigh, Ana Carolina Alves Mattos
Published 2010-07-01

New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

by Ciaran J. McCoy, Louise E. Atkinson, Mostafa Zamanian, Paul McVeigh, Tim A. Day, Michael J. Kimber, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Published 2014-06-01

RNAi effector diversity in nematodes.

by Johnathan J Dalzell, Paul McVeigh, Neil D Warnock, Makedonka Mitreva, David McK Bird, Pierre Abad, Colin C Fleming, Tim A Day, Angela Mousley, Nikki J Marks, Aaron G Maule
Published 2011-06-01

Stimulating Neoblast-Like Cell Proliferation in Juvenile Fasciola hepatica Supports Growth and Progression towards the Adult Phenotype In Vitro.

by Paul McCusker, Paul McVeigh, Vignesh Rathinasamy, Hayley Toet, Erin McCammick, Anna O'Connor, Nikki J Marks, Angela Mousley, Gerard P Brennan, David W Halton, Terry W Spithill, Aaron G Maule
Published 2016-09-01

RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development

by Paul McCusker, Wasim Hussain, Paul McVeigh, Erin McCammick, Nathan G. Clarke, Emily Robb, Fiona M. McKay, Peter M. Brophy, David J. Timson, Angela Mousley, Nikki J. Marks, Aaron G. Maule
Published 2020-12-01

RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.

by Paul McVeigh, Erin M McCammick, Paul McCusker, Russell M Morphew, Angela Mousley, Abbas Abidi, Khalid M Saifullah, Raman Muthusamy, Ravikumar Gopalakrishnan, Terry W Spithill, John P Dalton, Peter M Brophy, Nikki J Marks, Aaron G Maule
Published 2014-09-01

Phylum-Spanning Neuropeptide GPCR Identification and Prioritization: Shaping Drug Target Discovery Pipelines for Nematode Parasite Control

by Louise E. Atkinson, Ciaran J. McCoy, Bethany A. Crooks, Fiona M. McKay, Paul McVeigh, Darrin McKenzie, Allister Irvine, John Harrington, Bruce A. Rosa, Bruce A. Rosa, Makedonka Mitreva, Makedonka Mitreva, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Published 2021-09-01

Genomic insights into the origin of parasitism in the emerging plant pathogen Bursaphelenchus xylophilus.

by Taisei Kikuchi, James A Cotton, Jonathan J Dalzell, Koichi Hasegawa, Natsumi Kanzaki, Paul McVeigh, Takuma Takanashi, Isheng J Tsai, Samuel A Assefa, Peter J A Cock, Thomas Dan Otto, Martin Hunt, Adam J Reid, Alejandro Sanchez-Flores, Kazuko Tsuchihara, Toshiro Yokoi, Mattias C Larsson, Johji Miwa, Aaron G Maule, Norio Sahashi, John T Jones, Matthew Berriman
Published 2011-09-01