HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4.

by Richard C Hresko, Paul W Hruz
Published 2011-01-01

Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy.

by Arpita Kalla Vyas, Kai-Chien Yang, Dennis Woo, Anatoly Tzekov, Attila Kovacs, Patrick Y Jay, Paul W Hruz
Published 2011-02-01

Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia

by Monique R. Heitmeier, Maria A. Payne, Carla Weinheimer, Attila Kovacs, Richard C. Hresko, Patrick Y. Jay, Paul W. Hruz
Published 2018-04-01

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FL...

by Monique R Heitmeier, Richard C Hresko, Rachel L Edwards, Michael J Prinsen, Ma Xenia G Ilagan, Audrey R Odom John, Paul W Hruz
Published 2019-01-01

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

by Rachel L. Edwards, Robert C. Brothers, Xu Wang, Maxim I. Maron, Peter D. Ziniel, Patricia S. Tsang, Thomas E. Kraft, Paul W. Hruz, Kim C. Williamson, Cynthia S. Dowd, Audrey R. Odom John
Published 2017-08-01