Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair.

by Yearit Fridman, Niv Palgi, Daniel Dovrat, Shay Ben-Aroya, Philip Hieter, Amir Aharoni
Published 2010-10-01

Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair.

by Shay Ben-Aroya, Neta Agmon, Karen Yuen, Teresa Kwok, Kirk McManus, Martin Kupiec, Philip Hieter
Published 2010-02-01

Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip.

by Yujia A Chan, Maria J Aristizabal, Phoebe Y T Lu, Zongli Luo, Akil Hamza, Michael S Kobor, Peter C Stirling, Philip Hieter
Published 2014-04-01

Correction: An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

by Derek M. van Pel, Irene J. Barrett, Yoko Shimizu, Babu V. Sajesh, Brent J. Guppy, Tom Pfeifer, Kirk J. McManus, Philip Hieter
Published 2013-02-01

An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development.

by Derek M van Pel, Irene J Barrett, Yoko Shimizu, Babu V Sajesh, Brent J Guppy, Tom Pfeifer, Kirk J McManus, Philip Hieter
Published 2013-01-01

The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components.

by Peter C Stirling, Michelle S Bloom, Tejomayee Solanki-Patil, Stephanie Smith, Payal Sipahimalani, Zhijian Li, Megan Kofoed, Shay Ben-Aroya, Kyungjae Myung, Philip Hieter
Published 2011-04-01

Correction: An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development.

by Derek M. van Pel, Irene J. Barrett, Yoko Shimizu, Babu V. Sajesh, Brent J. Guppy, Tom Pfeifer, Kirk J. McManus, Philip Hieter
Published 2013-02-01

Synthetic lethality of cohesins with PARPs and replication fork mediators.

by Jessica L McLellan, Nigel J O'Neil, Irene Barrett, Elizabeth Ferree, Derek M van Pel, Kevin Ushey, Payal Sipahimalani, Jennifer Bryan, Ann M Rose, Philip Hieter
Published 2012-01-01

MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts

by Emily Yun-Chia Chang, Shuhe Tsai, Maria J. Aristizabal, James P. Wells, Yan Coulombe, Franciele F. Busatto, Yujia A. Chan, Arun Kumar, Yi Dan Zhu, Alan Ying-Hsu Wang, Louis-Alexandre Fournier, Philip Hieter, Michael S. Kobor, Jean-Yves Masson, Peter C. Stirling
Published 2019-09-01

Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A.

by Jessica C Price, Lana M Pollock, Meghan L Rudd, Sarah K Fogoros, Hassan Mohamed, Christin L Hanigan, Matthieu Le Gallo, NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program, Suiyuan Zhang, Pedro Cruz, Praveen F Cherukuri, Nancy F Hansen, Kirk J McManus, Andrew K Godwin, Dennis C Sgroi, James C Mullikin, Maria J Merino, Philip Hieter, Daphne W Bell
Published 2014-01-01

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5.

by Daphne W Bell, Nilabja Sikdar, Kyoo-Young Lee, Jessica C Price, Raghunath Chatterjee, Hee-Dong Park, Jennifer Fox, Masamichi Ishiai, Meghan L Rudd, Lana M Pollock, Sarah K Fogoros, Hassan Mohamed, Christin L Hanigan, NISC Comparative Sequencing Program, Suiyuan Zhang, Pedro Cruz, Gabriel Renaud, Nancy F Hansen, Praveen F Cherukuri, Bhavesh Borate, Kirk J McManus, Jan Stoepel, Payal Sipahimalani, Andrew K Godwin, Dennis C Sgroi, Maria J Merino, Gene Elliot, Abdel Elkahloun, Charles Vinson, Minoru Takata, James C Mullikin, Tyra G Wolfsberg, Philip Hieter, Dae-Sik Lim, Kyungjae Myung
Published 2011-08-01