Modified nucleic acids: replication, evolution, and next-generation therapeutics

by Karen Duffy, Sebastian Arangundy-Franklin, Philipp Holliger
Published 2020-09-01

Ribozyme-catalysed RNA synthesis using triplet building blocks

by James Attwater, Aditya Raguram, Alexey S Morgunov, Edoardo Gianni, Philipp Holliger
Published 2018-05-01

Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA.

by Samantha A Wynne, Vitor B Pinheiro, Philipp Holliger, Andrew G W Leslie
Published 2013-01-01

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

by Hannes Mutschler, Alexander I Taylor, Benjamin T Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet Herdewijn, Philipp Holliger
Published 2018-11-01

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

by Camille Samson, Pierre Legrand, Mustafa Tekpinar, Jef Rozenski, Mikhail Abramov, Philipp Holliger, Vitor B. Pinheiro, Piet Herdwijn, Marc Delarue
Published 2020-12-01