Marine Collagen Hydrolysates Downregulate the Synthesis of Pro-Catabolic and Pro-Inflammatory Markers of Osteoarthritis and Favor Collagen Production and Metabolic Activity in Equi...

by Bastien Bourdon, Romain Contentin, Frédéric Cassé, Chloé Maspimby, Sarah Oddoux, Antoine Noël, Florence Legendre, Nicolas Gruchy, Philippe Galéra
Published 2021-01-01

Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells.

by Séverine Cruet-Hennequart, Carole Drougard, Georgina Shaw, Florence Legendre, Magali Demoor, Frank Barry, Jean-Louis Lefaix, Philippe Galéra
Published 2015-01-01

RNA Interference and BMP-2 Stimulation Allows Equine Chondrocytes Redifferentiation in 3D-Hypoxia Cell Culture Model: Application for Matrix-Induced Autologous Chondrocyte Implanta...

by Rodolphe Rakic, Bastien Bourdon, Magalie Hervieu, Thomas Branly, Florence Legendre, Nathalie Saulnier, Fabrice Audigié, Stéphane Maddens, Magali Demoor, Philippe Galera
Published 2017-08-01

Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges

by Tangni Gómez-Leduc, Mélanie Desancé, Magalie Hervieu, Florence Legendre, David Ollitrault, Claire de Vienne, Michel Herlicoviez, Philippe Galéra, Magali Demoor
Published 2017-09-01

Marine Collagen Hydrolysates Promote Collagen Synthesis, Viability and Proliferation While Downregulating the Synthesis of Pro-Catabolic Markers in Human Articular Chondrocytes

by Bastien Bourdon, Frédéric Cassé, Nicolas Gruchy, Pierre Cambier, Sylvain Leclercq, Sarah Oddoux, Antoine Noël, Jérôme E. Lafont, Romain Contentin, Philippe Galéra
Published 2021-04-01

Enhanced chondrogenesis of bone marrow-derived stem cells by using a combinatory cell therapy strategy with BMP-2/TGF-β1, hypoxia, and COL1A1/HtrA1 siRNAs

by Florence Legendre, David Ollitrault, Tangni Gomez-Leduc, Mouloud Bouyoucef, Magalie Hervieu, Nicolas Gruchy, Frédéric Mallein-Gerin, Sylvain Leclercq, Magali Demoor, Philippe Galéra
Published 2017-06-01

Shell extracts from the marine bivalve Pecten maximus regulate the synthesis of extracellular matrix in primary cultured human skin fibroblasts.

by Thomas Latire, Florence Legendre, Nicolas Bigot, Ludovic Carduner, Sabrina Kellouche, Mouloud Bouyoucef, Franck Carreiras, Frédéric Marin, Jean-Marc Lebel, Philippe Galéra, Antoine Serpentini
Published 2014-01-01

Intra-Articular Injection of 2 Different Dosages of Autologous and Allogeneic Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cells Triggers a Variable Inflammatory Respon...

by Lélia Bertoni, Thomas Branly, Sandrine Jacquet, Mélanie Desancé, Loïc Desquilbet, Pascaline Rivory, Daniel-Jean Hartmann, Jean-Marie Denoix, Fabrice Audigié, Philippe Galéra, Magali Demoor
Published 2019-01-01

Improvement of the Chondrocyte-Specific Phenotype upon Equine Bone Marrow Mesenchymal Stem Cell Differentiation: Influence of Culture Time, Transforming Growth Factors and Type I C...

by Thomas Branly, Romain Contentin, Mélanie Desancé, Thibaud Jacquel, Lélia Bertoni, Sandrine Jacquet, Frédéric Mallein-Gerin, Jean-Marie Denoix, Fabrice Audigié, Magali Demoor, Philippe Galéra
Published 2018-02-01

Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids

by Clément Veys, Abderrahim Benmoussa, Romain Contentin, Amandine Duchemin, Emilie Brotin, Jérôme E. Lafont, Yannick Saintigny, Laurent Poulain, Christophe Denoyelle, Magali Demoor, Florence Legendre, Philippe Galéra
Published 2021-05-01

Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy

by Mélanie Desancé, Romain Contentin, Lélia Bertoni, Tangni Gomez-Leduc, Thomas Branly, Sandrine Jacquet, Jean-Marc Betsch, Agnès Batho, Florence Legendre, Fabrice Audigié, Philippe Galéra, Magali Demoor
Published 2018-02-01

An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopi...

by Lélia Bertoni, Sandrine Jacquet-Guibon, Thomas Branly, Florence Legendre, Mélanie Desancé, Céline Mespoulhes, Martine Melin, Daniel-Jean Hartmann, Amandine Schmutz, Jean-Marie Denoix, Philippe Galéra, Magali Demoor, Fabrice Audigié
Published 2020-01-01

Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model

by Lélia Bertoni, Sandrine Jacquet-Guibon, Thomas Branly, Mélanie Desancé, Florence Legendre, Martine Melin, Pascaline Rivory, Daniel-Jean Hartmann, Amandine Schmutz, Jean-Marie Denoix, Magali Demoor, Fabrice Audigié, Philippe Galéra
Published 2021-03-01