A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins

by Pierre Chapdelaine, Zoé Coulombe, Amina Chikh, Catherine Gérard, Jacques P Tremblay
Published 2013-01-01

Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag

by Khadija Cherif, Catherine Gérard, Joël Rousseau, Dominique L. Ouellet, Pierre Chapdelaine, Jacques P. Tremblay
Published 2018-09-01

Abnormal prostaglandin E2 production blocks myogenic differentiation in myotonic dystrophy

by Daniel Beaulieu, Philippe Thebault, Richard Pelletier, Pierre Chapdelaine, Mark Tarnopolsky, Denis Furling, Jack Puymirat
Published 2012-01-01

Inhibiting Myostatin with Follistatin Improves the Success of Myoblast Transplantation in Dystrophic Mice

by Basma F. Benabdallah, Manaf Bouchentouf, Joel Rousseau, Pascal Bigey, Annick Michaud, Pierre Chapdelaine, Daniel Scherman, Jacques P. Tremblay
Published 2008-03-01

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method

by Jean-Paul Iyombe-Engembe, Dominique L Ouellet, Xavier Barbeau, Joël Rousseau, Pierre Chapdelaine, Patrick Lagüe, Jacques P Tremblay
Published 2016-01-01

Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation

by Basma F Benabdallah, Arnaud Duval, Joel Rousseau, Pierre Chapdelaine, Michael C Holmes, Eli Haddad, Jacques P Tremblay, Christian M Beauséjour
Published 2013-01-01

An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models

by Catherine Gérard, Xiao Xiao, Mohammed Filali, Zoé Coulombe, Marie Arsenault, Jacques Couet, Juan Li, Marie-Claude Drolet, Pierre Chapdelaine, Amina Chikh, Jacques P Tremblay
Published 2014-01-01