Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson’s Disease and Synucleinopathies

by Cristine Betzer, Cristine Betzer, Poul Henning Jensen, Poul Henning Jensen
Published 2018-11-01

Organotypic hippocampal slices, an emerging tool to model synucleinopathies

by Sara Elfarrash, Poul Henning Jensen
Published 2021-01-01

Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2- and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein

by Rikke H. Kofoed, Cristine Betzer, Nelson Ferreira, Poul Henning Jensen
Published 2020-03-01

The Prion-Like Spreading of Alpha-Synuclein in Parkinson’s Disease: Update on Models and Hypotheses

by Asad Jan, Nádia Pereira Gonçalves, Christian Bjerggaard Vaegter, Poul Henning Jensen, Nelson Ferreira
Published 2021-08-01

Stabilization of α-synuclein oligomers using formaldehyde.

by Harm Ruesink, Lasse Reimer, Emil Gregersen, Arne Moeller, Cristine Betzer, Poul Henning Jensen
Published 2019-01-01

Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein.

by Cristine Betzer, A James Movius, Min Shi, Wei-Ping Gai, Jing Zhang, Poul Henning Jensen
Published 2015-01-01

ELISA method to detect α-synuclein oligomers in cell and animal models.

by Louise Berkhoudt Lassen, Emil Gregersen, Anne Kathrine Isager, Cristine Betzer, Rikke Hahn Kofoed, Poul Henning Jensen
Published 2018-01-01

Prodegenerative IκBα expression in oligodendroglial α-synuclein models of multiple system atrophy

by Christine L. Kragh, Amanda M. Gysbers, Edward Rockenstein, Karen Murphy, Glenda M. Halliday, Eliezer Masliah, Poul Henning Jensen
Published 2014-03-01

Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

by Emil Gregersen, Cristine Betzer, Woojin S. Kim, Gergo Kovacs, Lasse Reimer, Glenda M. Halliday, Steffen Thiel, Poul Henning Jensen
Published 2021-08-01

CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology

by Mads N. Olesen, Josefine R. Christiansen, Steen Vang Petersen, Poul Henning Jensen, Wojciech Paslawski, Marina Romero-Ramos, Vanesa Sanchez-Guajardo
Published 2018-01-01

Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation

by Michael Aagaard Andersen, Kenneth Vielsted Christensen, Lassina Badolo, Garrick Paul Smith, Ross Jeggo, Poul Henning Jensen, Kathrine Just Andersen, Florence Sotty
Published 2018-08-01

Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain

by Nelson Ferreira, Nádia Pereira Gonçalves, Asad Jan, Nanna Møller Jensen, Amelia van der Laan, Simin Mohseni, Christian Bjerggaard Vægter, Poul Henning Jensen
Published 2021-02-01

Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study

by Hua Wang, Anzari Atik, Tessandra Stewart, Carmen Ginghina, Patrick Aro, Kathleen F. Kerr, John Seibyl, Danna Jennings, Poul Henning Jensen, Kenneth Marek, Min Shi, Jing Zhang
Published 2018-08-01

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.

by Carmela Matrone, Nicolas Dzamko, Peder Madsen, Mette Nyegaard, Regina Pohlmann, Rikke V Søndergaard, Louise B Lassen, Thomas L Andresen, Glenda M Halliday, Poul Henning Jensen, Morten S Nielsen
Published 2016-01-01

Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death

by Lasse Reimer, Louise Buur Vesterager, Cristine Betzer, Jin Zheng, Lærke Dalsgaard Nielsen, Rikke Hahn Kofoed, Louise Berkhoudt Lassen, Ulrik Bølcho, Søren Riis Paludan, Karina Fog, Poul Henning Jensen
Published 2018-07-01

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates

by Sara Elfarrash, Nanna Møller Jensen, Nelson Ferreira, Cristine Betzer, Jervis Vermal Thevathasan, Robin Diekmann, Mohamed Adel, Nisreen Mansour Omar, Mohamed Z. Boraie, Sabry Gad, Jonas Ries, Deniz Kirik, Sadegh Nabavi, Poul Henning Jensen
Published 2019-12-01

Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

by Gábor G. Kovács, Lajos László, János Kovács, Poul Henning Jensen, Evo Lindersson, Gergő Botond, Tamás Molnár, András Perczel, Ferenc Hudecz, Gábor Mező, Anna Erdei, László Tirián, Attila Lehotzky, Ellen Gelpi, Herbert Budka, Judit Ovádi
Published 2004-11-01

Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease

by Luis M. A. Oliveira, Thomas Gasser, Robert Edwards, Markus Zweckstetter, Ronald Melki, Leonidas Stefanis, Hilal A. Lashuel, David Sulzer, Kostas Vekrellis, Glenda M. Halliday, Julianna J. Tomlinson, Michael Schlossmacher, Poul Henning Jensen, Julia Schulze-Hentrich, Olaf Riess, Warren D. Hirst, Omar El-Agnaf, Brit Mollenhauer, Peter Lansbury, Tiago F. Outeiro
Published 2021-07-01