Genetic Factors in Animal Models of Intestinal Inflammation

by R Balfour Sartor
Published 1995-01-01

Antibacterial Therapy of Inflammation Bowel Disease: Implications for Pathogenesis and Management

by R Balfour Sartor
Published 1993-01-01

Lessons in IBD Pathogenesis from New Animal Models of Spontaneous Colitis

by R Balfour Sartor
Published 1995-01-01

Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic Mice

by Allison R. Rogala, Allison R. Rogala, Akihiko Oka, R. Balfour Sartor, R. Balfour Sartor
Published 2020-02-01

Resident Bacteria-Stimulated Interleukin-10-Secreting B Cells Ameliorate T-Cell-Mediated Colitis by Inducing T-Regulatory-1 Cells That Require Interleukin-27 SignalingSummary

by Yoshiyuki Mishima, Bo Liu, Jonathan J. Hansen, R. Balfour Sartor
Published 2015-05-01

Small heat-shock proteins, IbpAB, protect non-pathogenic Escherichia coli from killing by macrophage-derived reactive oxygen species.

by Laura Goeser, Ting-Jia Fan, Sandrine Tchaptchet, Nikolas Stasulli, William E Goldman, R Balfour Sartor, Jonathan J Hansen
Published 2015-01-01

The colitis-associated transcriptional profile of commensal Bacteroides thetaiotaomicron enhances adaptive immune responses to a bacterial antigen.

by Jonathan J Hansen, Yong Huang, Daniel A Peterson, Laura Goeser, Ting-Jia Fan, Eugene B Chang, R Balfour Sartor
Published 2012-01-01

Phosphoinositide 3-Kinase P110δ-Signaling Is Critical for Microbiota-Activated IL-10 Production by B Cells that Regulate Intestinal Inflammation

by Akihiko Oka, Yoshiyuki Mishima, Bo Liu, Jeremy W. Herzog, Erin C. Steinbach, Taku Kobayashi, Scott E. Plevy, R. Balfour Sartor
Published 2019-09-01

Mouse background strain profoundly influences Paneth cell function and intestinal microbial composition.

by Ajay S Gulati, Michael T Shanahan, Janelle C Arthur, Emily Grossniklaus, Richard J von Furstenberg, Lieselotte Kreuk, Susan J Henning, Christian Jobin, R Balfour Sartor
Published 2012-01-01

Complex Bacterial Consortia Reprogram the Colitogenic Activity of Enterococcus faecalis in a Gnotobiotic Mouse Model of Chronic, Immune-Mediated Colitis

by Isabella Lengfelder, Irina G. Sava, Jonathan J. Hansen, Karin Kleigrewe, Jeremy Herzog, Klaus Neuhaus, Klaus Neuhaus, Thomas Hofmann, Thomas Hofmann, R. Balfour Sartor, Dirk Haller, Dirk Haller
Published 2019-06-01

Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice

by Melissa Ellermann, Raad Z. Gharaibeh, Nitsan Maharshak, Ernesto Peréz-Chanona, Christian Jobin, Ian M. Carroll, Janelle C. Arthur, Scott E Plevy, Anthony A. Fodor, Cory R. Brouwer, R. Balfour Sartor
Published 2020-01-01

Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice

by Allison R. Rogala, Alexi A. Schoenborn, Brian E. Fee, Viviana A. Cantillana, Maria J. Joyce, Raad Z. Gharaibeh, Sayanty Roy, Anthony A. Fodor, R. Balfour Sartor, Gregory A. Taylor, Ajay S. Gulati
Published 2018-02-01

Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels.

by Soeren Ocvirk, Irina G Sava, Isabella Lengfelder, Ilias Lagkouvardos, Natalie Steck, Jung H Roh, Sandrine Tchaptchet, Yinyin Bao, Jonathan J Hansen, Johannes Huebner, Ian M Carroll, Barbara E Murray, R Balfour Sartor, Dirk Haller
Published 2015-06-01

Influence of Crohn's disease related polymorphisms in innate immune function on ileal microbiome.

by Ellen Li, Yuanhao Zhang, Xinyu Tian, Xuefeng Wang, Grace Gathungu, Ashley Wolber, Shehzad S Shiekh, R Balfour Sartor, Nicholas O Davidson, Matthew A Ciorba, Wei Zhu, Leah M Nelson, Charles E Robertson, Daniel N Frank
Published 2019-01-01

Rationally designed bacterial consortia to treat chronic immune-mediated colitis and restore intestinal homeostasis

by Daniel van der Lelie, Akihiko Oka, Safiyh Taghavi, Junji Umeno, Ting-Jia Fan, Katherine E. Merrell, Sarah D. Watson, Lisa Ouellette, Bo Liu, Muyiwa Awoniyi, Yunjia Lai, Liang Chi, Kun Lu, Christopher S. Henry, R. Balfour Sartor
Published 2021-05-01

The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse.

by Andrew P Morgan, James J Crowley, Randal J Nonneman, Corey R Quackenbush, Cheryl N Miller, Allison K Ryan, Molly A Bogue, Sur Herrera Paredes, Scott Yourstone, Ian M Carroll, Thomas H Kawula, Maureen A Bower, R Balfour Sartor, Patrick F Sullivan
Published 2014-01-01

Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition.

by Ellen Li, Christina M Hamm, Ajay S Gulati, R Balfour Sartor, Hongyan Chen, Xiao Wu, Tianyi Zhang, F James Rohlf, Wei Zhu, Chi Gu, Charles E Robertson, Norman R Pace, Edgar C Boedeker, Noam Harpaz, Jeffrey Yuan, George M Weinstock, Erica Sodergren, Daniel N Frank
Published 2012-01-01

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3

by Cun-Jin Zhang, Chenhui Wang, Meiling Jiang, Chunfang Gu, Jianxin Xiao, Xing Chen, Bradley N. Martin, Fangqiang Tang, Erin Yamamoto, Yibo Xian, Han Wang, Fengling Li, R. Balfour Sartor, Howard Smith, M. Elaine Husni, Fu-Dong Shi, Ji Gao, Julie Carman, Ashok Dongre, Susan C. McKarns, Ken Coppieters, Trine N. Jørgensen, Warren J. Leonard, Xiaoxia Li
Published 2018-07-01