Keep Your Friends Close, but Your Enemies Closer: Role of Acid Sphingomyelinase During Infection and Host Response

by Ha-Yeun Chung, Ha-Yeun Chung, Ralf A. Claus
Published 2021-01-01

Attenuated inflammatory response in aged mice brains following stroke.

by Matthias W Sieber, Ralf A Claus, Otto W Witte, Christiane Frahm
Published 2011-01-01

Sphingolipidomics in Translational Sepsis Research–Biomedical Considerations and Perspectives

by Ralf A. Claus, Markus H. Graeler, Markus H. Graeler, Markus H. Graeler
Published 2021-01-01

Alternative splicing of SMPD1 in human sepsis.

by Marcel Kramer, Stefanie Quickert, Christoph Sponholz, Uwe Menzel, Klaus Huse, Matthias Platzer, Michael Bauer, Ralf A Claus
Published 2015-01-01

Alternative 5' untranslated regions are involved in expression regulation of human heme oxygenase-1.

by Marcel Kramer, Christoph Sponholz, Monique Slaba, Bianka Wissuwa, Ralf A Claus, Uwe Menzel, Klaus Huse, Matthias Platzer, Michael Bauer
Published 2013-01-01

Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis

by Ha-Yeun Chung, C. Julius Witt, Jorge Hurtado-Oliveros, Jonathan Wickel, Markus H. Gräler, Amelie Lupp, Ralf A. Claus
Published 2018-10-01

Plasma Neutrophil Gelatinase-Associated Lipocalin Is Primarily Related to Inflammation during Sepsis: A Translational Approach.

by Gordon P Otto, Jorge Hurtado-Oliveros, Ha-Yeun Chung, Kristin Knoll, Thomas Neumann, Hans J Müller, Marco Herbsleb, Matthias Kohl, Martin Busch, Maik Sossdorf, Ralf A Claus
Published 2015-01-01

Hyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response

by Nayla Jbeily, Iris Suckert, Falk A. Gonnert, Benedikt Acht, Clemens L. Bockmeyer, Sascha D. Grossmann, Markus F. Blaess, Anja Lueth, Hans-Peter Deigner, Michael Bauer, Ralf A. Claus
Published 2013-02-01

Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis

by Ha-Yeun Chung, Daniel C Hupe, Gordon P Otto, Marcel Sprenger, Alexander C Bunck, Michael J Dorer, Clemens L Bockmeyer, Hans-Peter Deigner, Markus H Gräler, Ralf A Claus
Published 2016-06-01

Combination of Classifiers Identifies Fungal-Specific Activation of Lysosome Genes in Human Monocytes

by João P. Leonor Fernandes Saraiva, João P. Leonor Fernandes Saraiva, Cristina Zubiria-Barrera, Tilman E. Klassert, Maximilian J. Lautenbach, Markus Blaess, Ralf A. Claus, Hortense Slevogt, Rainer König, Rainer König
Published 2017-11-01

Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in SepsisResearch in context

by Yvonn Heun, Joachim Pircher, Thomas Czermak, Philipp Bluem, Georg Hupel, Monica Bohmer, Bjoern F. Kraemer, Kristin Pogoda, Alexander Pfeifer, Markus Woernle, Andrea Ribeiro, Max Hübner, Simone Kreth, Ralf A. Claus, Sebastian Weis, Luisa Ungelenk, Florian Krötz, Ulrich Pohl, Hanna Mannell
Published 2019-04-01

Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis.

by Peter Recknagel, Falk A Gonnert, Martin Westermann, Sandro Lambeck, Amelie Lupp, Alain Rudiger, Alex Dyson, Jane E Carré, Andreas Kortgen, Christoph Krafft, Jürgen Popp, Christoph Sponholz, Valentin Fuhrmann, Ingrid Hilger, Ralf A Claus, Niels C Riedemann, Reinhard Wetzker, Mervyn Singer, Michael Trauner, Michael Bauer
Published 2012-01-01

Use of IFNγ/IL10 Ratio for Stratification of Hydrocortisone Therapy in Patients With Septic Shock

by Rainer König, Rainer König, Amol Kolte, Amol Kolte, Olaf Ahlers, Marcus Oswald, Marcus Oswald, Veiko Krauss, Veiko Krauss, Daniela Roell, Daniela Roell, Oliver Sommerfeld, George Dimopoulos, Iraklis Tsangaris, Eleni Antoniadou, Neeraja Jaishankar, Holger Bogatsch, Markus Löffler, Markus Rödel, Marina Garcia-Moreno, Lorena Tuchscherr, Charles L. Sprung, Mervyn Singer, Frank Brunkhorst, Michael Oppert, Herwig Gerlach, Ralf A. Claus, Sina M. Coldewey, Sina M. Coldewey, Sina M. Coldewey, Josef Briegel, Evangelos J. Giamarellos-Bourboulis, Evangelos J. Giamarellos-Bourboulis, Didier Keh, Michael Bauer, Michael Bauer
Published 2021-03-01