Development of an antibiotic marker-free platform for heterologous protein production in Streptomyces

by Laura Sevillano, Margarita Díaz, Ramón I. Santamaría
Published 2017-09-01

Identification of the first functional toxin-antitoxin system in Streptomyces.

by Laura Sevillano, Margarita Díaz, Yoshihiro Yamaguchi, Masayori Inouye, Ramón I Santamaría
Published 2012-01-01

Novel two-component systems implied in antibiotic production in Streptomyces coelicolor.

by Ana Yepes, Sergio Rico, Antonio Rodríguez-García, Ramón I Santamaría, Margarita Díaz
Published 2011-01-01

The XRE-DUF397 Protein Pair, Scr1 and Scr2, Acts as a Strong Positive Regulator of Antibiotic Production in Streptomyces

by Ramón I. Santamaría, Laura Sevillano, Jesús Martín, Olga Genilloud, Ignacio González, Margarita Díaz
Published 2018-11-01

Antibiotic Production and Antibiotic Resistance: The Two Sides of AbrB1/B2, a Two-Component System of Streptomyces coelicolor

by Ricardo Sánchez de la Nieta, Sergio Antoraz, Juan F. Alzate, Ramón I. Santamaría, Margarita Díaz
Published 2020-10-01

Regulation of the AbrA1/A2 two-component system in Streptomyces coelicolor and the potential of its deletion strain as a heterologous host for antibiotic production.

by Sergio Rico, Ana Yepes, Héctor Rodríguez, Jorge Santamaría, Sergio Antoraz, Eva M Krause, Margarita Díaz, Ramón I Santamaría
Published 2014-01-01

The Orphan Response Regulator Aor1 Is a New Relevant Piece in the Complex Puzzle of Streptomyces coelicolor Antibiotic Regulatory Network

by Sergio Antoraz, Sergio Rico, Héctor Rodríguez, Héctor Rodríguez, Laura Sevillano, Juan F. Alzate, Ramón I. Santamaría, Margarita Díaz
Published 2017-12-01

Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches.

by Adriana Becerril, Susana Álvarez, Alfredo F Braña, Sergio Rico, Margarita Díaz, Ramón I Santamaría, José A Salas, Carmen Méndez
Published 2018-01-01

The two kinases, AbrC1 and AbrC2, of the atypical two-component system AbrC are needed to regulate antibiotic production and differentiation in Streptomyces coelicolor.

by Héctor eRodríguez, Sergio eRico, Ana eYepes, Elsa eFranco-Echeverría, Sergio eAntoraz, Ramón I Santamaría, Margarita eDíaz
Published 2015-05-01

Characterization of Actinomycetes Strains Isolated from the Intestinal Tract and Feces of the Larvae of the Longhorn Beetle <i>Cerambyx welensii</i>

by Ramón I. Santamaría, Ana Martínez-Carrasco, Ricardo Sánchez de la Nieta, Luis M. Torres-Vila, Raúl Bonal, Jesús Martín, Rubén Tormo, Fernando Reyes, Olga Genilloud, Margarita Díaz
Published 2020-12-01