Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q.

by Svetlana Pidasheva, Sara Trifari, Anne Phillips, Jason A Hackney, Yan Ma, Ashley Smith, Sue J Sohn, Hergen Spits, Randall D Little, Timothy W Behrens, Lee Honigberg, Nico Ghilardi, Hilary F Clark
Published 2011-01-01

Systematic association mapping identifies NELL1 as a novel IBD disease gene.

by Andre Franke, Jochen Hampe, Philip Rosenstiel, Christian Becker, Florian Wagner, Robert Häsler, Randall D Little, Klaus Huse, Andreas Ruether, Tobias Balschun, Michael Wittig, Abdou Elsharawy, Gabriele Mayr, Mario Albrecht, Natalie J Prescott, Clive M Onnie, Hélène Fournier, Tim Keith, Uwe Radelof, Matthias Platzer, Christopher G Mathew, Monika Stoll, Michael Krawczak, Peter Nürnberg, Stefan Schreiber
Published 2007-08-01