2 (2 amino 1,3 thiazol 4 yl)acetohydrazide 2 [2 (2 amino 1,3 thiazol 4 yl)acetyl] n phenyl 1 hydrazinecarbothioamide 2-Aminothiazole 4 ({5 [(4 chlorophenyl)sulfanyl 4 phenyl 4h 1,2,4 triazol 3 yl}methyl) 1,3 thiazol 2 amine 5 [(2 amino 1,3 thiazol 4 yl)methyl] 4 phenyl 4h 1,2,4 triazole 3 thiol Anti-proliferation Article B16-F10 cell line MTT assay Matrix metalloproteinase Triazole Zymography animal cell antineoplastic activity antiproliferative activity biochemical analysis biological activity blood brain barrier carbon nuclear magnetic resonance cell assay cell viability chemical structure controlled study drug absorption drug bioavailability drug synthesis elemental analysis heterocyclic compound infrared spectroscopy intestine absorption