Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

by Reisman SA, Gahir SS, Lee CY, Proksch JW, Sakamoto M, Ward KW
Published 2019-04-01

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

by Creelan BC, Gabrilovich DI, Gray JE, Williams CC, Tanvetyanon T, Haura EB, Weber JS, Gibney GT, Markowitz J, Proksch JW, Reisman SA, McKee MD, Chin MP, Meyer CJ, Antonia SJ
Published 2017-08-01