An optimized CRISPR/Cas9 approach for precise genome editing in neurons

by Huaqiang Fang, Alexei M Bygrave, Richard H Roth, Richard C Johnson, Richard L Huganir
Published 2021-03-01

Lamina-specific AMPA receptor dynamics following visual deprivation in vivo

by Han L Tan, Richard H Roth, Austin R Graves, Robert H Cudmore, Richard L Huganir
Published 2020-03-01

DGKθ Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses

by Hana L. Goldschmidt, Becky Tu-Sekine, Lenora Volk, Victor Anggono, Richard L. Huganir, Daniel M. Raben
Published 2016-01-01

SynGAP isoforms differentially regulate synaptic plasticity and dendritic development

by Yoichi Araki, Ingie Hong, Timothy R Gamache, Shaowen Ju, Leonardo Collado-Torres, Joo Heon Shin, Richard L Huganir
Published 2020-06-01

High-Throughput Genetic Screen for Synaptogenic Factors: Identification of LRP6 as Critical for Excitatory Synapse Development

by Kamal Sharma, Se-Young Choi, Yong Zhang, Thomas J.F. Nieland, Shunyou Long, Min Li, Richard L. Huganir
Published 2013-12-01

Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum

by Rebeca Mejias, Shu-Ling Chiu, Mei Han, Rebecca Rose, Ana Gil-Infante, Yifan Zhao, Richard L. Huganir, Tao Wang
Published 2019-12-01

Activity-Dependent Ubiquitination of GluA1 and GluA2 Regulates AMPA Receptor Intracellular Sorting and Degradation

by Jocelyn Widagdo, Ye Jin Chai, Margreet C. Ridder, Yu Qian Chau, Richard C. Johnson, Pankaj Sah, Richard L. Huganir, Victor Anggono
Published 2015-02-01

Phosphorylation of AMPA receptors is required for sensory deprivation-induced homeostatic synaptic plasticity.

by Anubhuti Goel, Linda W Xu, Kevin P Snyder, Lihua Song, Yamila Goenaga-Vazquez, Andrea Megill, Kogo Takamiya, Richard L Huganir, Hey-Kyoung Lee
Published 2011-03-01

DlgS97/SAP97, a neuronal isoform of discs large, regulates ethanol tolerance.

by Rajani Maiya, Seonok Lee, Karen H Berger, Eric C Kong, Justin B Slawson, Leslie C Griffith, Kogo Takamiya, Richard L Huganir, Ben Margolis, Ulrike Heberlein
Published 2012-01-01

Involvement of AMPA receptor GluR2 and GluR3 trafficking in trigeminal spinal subnucleus caudalis and C1/C2 neurons in acute-facial inflammatory pain.

by Makiko Miyamoto, Yoshiyuki Tsuboi, Kuniya Honda, Masayuki Kobayashi, Kogo Takamiya, Richard L Huganir, Masahiro Kondo, Masamichi Shinoda, Barry J Sessle, Ayano Katagiri, Daiju Kita, Ikuko Suzuki, Yoshiyuki Oi, Koichi Iwata
Published 2012-01-01

Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division

by Kie Itoh, Daisuke Murata, Takashi Kato, Tatsuya Yamada, Yoichi Araki, Atsushi Saito, Yoshihiro Adachi, Atsushi Igarashi, Shuo Li, Mikhail Pletnikov, Richard L Huganir, Shigeki Watanabe, Atsushi Kamiya, Miho Iijima, Hiromi Sesaki
Published 2019-10-01

Affected Sib-Pair Analyses Identify Signaling Networks Associated With Social Behavioral Deficits in Autism

by Mehdi Pirooznia, Mehdi Pirooznia, Tejasvi Niranjan, Yun-Ching Chen, Ilker Tunc, Fernando S. Goes, Dimitrios Avramopoulos, Dimitrios Avramopoulos, James B. Potash, Richard L. Huganir, Peter P. Zandi, Peter P. Zandi, Tao Wang
Published 2019-11-01

Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold.

by Roberta Noseda, Marta Guerrero-Valero, Valeria Alberizzi, Stefano C Previtali, Diane L Sherman, Marilena Palmisano, Richard L Huganir, Klaus-Armin Nave, Ana Cuenda, Maria Laura Feltri, Peter J Brophy, Alessandra Bolino
Published 2016-04-01

Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas

by Lili Li, Yichao Fan, Xin Huang, Jie Luo, Lan Zhong, Xing-sheng Shu, Li Lu, Tingxiu Xiang, Anthony T.C. Chan, Winnie Yeo, Ceshi Chen, Wai Yee Chan, Richard L. Huganir, Qian Tao
Published 2019-11-01

Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice

by Rebeca Mejias, Juan J. Rodriguez-Gotor, Minae Niwa, Irina N. Krasnova, Abby Adamczyk, Mei Han, Gareth M. Thomas, Zheng-Xiong Xi, Richard L. Huganir, Mikhail V. Pletnikov, Akira Sawa, Jean-Lud Cadet, Tao Wang
Published 2021-01-01

Characterization of in vivo Dlg1 deletion on T cell development and function.

by Lisa A Humphries, Meredith H Shaffer, Faruk Sacirbegovic, Tamar Tomassian, Kerrie-Ann McMahon, Patrick O Humbert, Oscar Silva, June L Round, Kogo Takamiya, Richard L Huganir, Janis K Burkhardt, Sarah M Russell, M Carrie Miceli
Published 2012-01-01