The Challenges of Genome Analysis in the Health Care Setting

by Anneke Lucassen, Richard S. Houlston
Published 2014-07-01

Architecture of Inherited Susceptibility to Colorectal Cancer: A Voyage of Discovery

by Nicola Whiffin, Richard S. Houlston
Published 2014-03-01

Constitutional mutation in CDKN2A is associated with long term survivorship in multiple myeloma: a case report

by Vallari Shah, Kevin D. Boyd, Richard S. Houlston, Martin F. Kaiser
Published 2017-11-01

Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk.

by Yufei Wang, Peter Broderick, Athena Matakidou, Timothy Eisen, Richard S Houlston
Published 2011-04-01

visPIG--a web tool for producing multi-region, multi-track, multi-scale plots of genetic data.

by Matthew Scales, Roland Jäger, Gabriele Migliorini, Richard S Houlston, Marc Y R Henrion
Published 2014-01-01

Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2

by James B. Studd, Jayaram Vijayakrishnan, Minjun Yang, Gabriele Migliorini, Kajsa Paulsson, Richard S. Houlston
Published 2017-03-01

Correction: Author Correction: Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2

by James B. Studd, Jayaram Vijayakrishnan, Minjun Yang, Gabriele Migliorini, Kajsa Paulsson, Richard S. Houlston
Published 2018-05-01

A novel test for gene-ancestry interactions in genome-wide association data.

by Joanna L Davies, Jean-Baptiste Cazier, Malcolm G Dunlop, Richard S Houlston, Ian P Tomlinson, Chris C Holmes
Published 2012-01-01

A retrospective observational study of the relationship between single nucleotide polymorphisms associated with the risk of developing colorectal cancer and survival.

by Eva J A Morris, Steve Penegar, Nicola Whiffin, Peter Broderick, D Timothy Bishop, Emma Northwood, Philip Quirke, Paul Finan, Richard S Houlston
Published 2015-01-01

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression

by Ni Li, David C. Johnson, Niels Weinhold, James B. Studd, Giulia Orlando, Fabio Mirabella, Jonathan S. Mitchell, Tobias Meissner, Martin Kaiser, Hartmut Goldschmidt, Kari Hemminki, Gareth J. Morgan, Richard S. Houlston
Published 2016-11-01

HLA associations in classical Hodgkin lymphoma: EBV status matters.

by Xin Huang, Kushi Kushekhar, Ilja Nolte, Wierd Kooistra, Lydia Visser, Ilby Bouwman, Niels Kouprie, Rianne Veenstra, Gustaaf van Imhoff, Bianca Olver, Richard S Houlston, Sibrand Poppema, Arjan Diepstra, Bouke Hepkema, Anke van den Berg
Published 2012-01-01

Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer

by Daniel Chubb, Peter Broderick, Sara E. Dobbins, Matthew Frampton, Ben Kinnersley, Steven Penegar, Amy Price, Yussanne P. Ma, Amy L. Sherborne, Claire Palles, Maria N. Timofeeva, D. Timothy Bishop, Malcolm G. Dunlop, Ian Tomlinson, Richard S. Houlston
Published 2016-06-01

Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility

by Kevin Litchfield, Max Levy, Darshna Dudakia, Paula Proszek, Claire Shipley, Sander Basten, Elizabeth Rapley, D. Timothy Bishop, Alison Reid, Robert Huddart, Peter Broderick, David Gonzalez de Castro, Simon O'Connor, Rachel H. Giles, Richard S. Houlston, Clare Turnbull
Published 2016-12-01

The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression

by Ning Qing Liu, Menno ter Huurne, Luan N. Nguyen, Tianran Peng, Shuang-Yin Wang, James B. Studd, Onkar Joshi, Halit Ongen, Jesper B Bramsen, Jian Yan, Claus L. Andersen, Jussi Taipale, Emmanouil T. Dermitzakis, Richard S. Houlston, Nina C. Hubner, Hendrik G. Stunnenberg
Published 2017-02-01

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

by Helen E. Speedy, Renée Beekman, Vicente Chapaprieta, Giulia Orlando, Philip J. Law, David Martín-García, Jesús Gutiérrez-Abril, Daniel Catovsky, Sílvia Beà, Guillem Clot, Montserrat Puiggròs, David Torrents, Xose S. Puente, James M. Allan, Carlos López-Otín, Elias Campo, Richard S. Houlston, José I. Martín-Subero
Published 2019-08-01

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

by Radhika Kandaswamy, Georgina P. Sava, Helen E. Speedy, Sílvia Beà, José I. Martín-Subero, James B. Studd, Gabriele Migliorini, Philip J. Law, Xose S. Puente, David Martín-García, Itziar Salaverria, Jesús Gutiérrez-Abril, Carlos López-Otín, Daniel Catovsky, James M. Allan, Elías Campo, Richard S. Houlston
Published 2016-08-01

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

by Alan M Pittman, Silvia Naranjo, Sanni E Jalava, Philip Twiss, Yussanne Ma, Bianca Olver, Amy Lloyd, Jayaram Vijayakrishnan, Mobshra Qureshi, Peter Broderick, Tom van Wezel, Hans Morreau, Sari Tuupanen, Lauri A Aaltonen, M Eva Alonso, Miguel Manzanares, Angela Gavilán, Tapio Visakorpi, José Luis Gómez-Skarmeta, Richard S Houlston
Published 2010-09-01

Meta-Analyses of Splicing and Expression Quantitative Trait Loci Identified Susceptibility Genes of Glioma

by C. Pawan K. Patro, Darryl Nousome, The Glioma International Case Control Study (GICC), Rose K. Lai, Elizabeth B. Claus, Dora Il’yasova, Joellen Schildkraut, Jill S. Barnholtz-Sloan, Sara H. Olson, Jonine L. Bernstein, Christoffer Johansen, Robert B. Jenkins, Beatrice S. Melin, Margaret R. Wrensch, Richard S. Houlston, Melissa L. Bondy
Published 2021-04-01

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

by Yun Feng, Yanru Wang, Hongliang Liu, Zhensheng Liu, Coleman Mills, Younghun Han, Rayjean J. Hung, Yonathan Brhane, John McLaughlin, Paul Brennan, Heike Bickeboeller, Albert Rosenberger, Richard S. Houlston, Neil E. Caporaso, Maria Teresa Landi, Irene Brueske, Angela Risch, Yuanqing Ye, Xifeng Wu, David C. Christiani, Christopher I. Amos, Qingyi Wei
Published 2017-04-01

Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma

by David C. Johnson, Niels Weinhold, Jonathan S. Mitchell, Bowang Chen, Martin Kaiser, Dil B. Begum, Jens Hillengass, Uta Bertsch, Walter A. Gregory, David Cairns, Graham H. Jackson, Asta Försti, Jolanta Nickel, Per Hoffmann, Markus M. Nöethen, Owen W. Stephens, Bart Barlogie, Faith E. Davis, Kari Hemminki, Hartmut Goldschmidt, Richard S. Houlston, Gareth J. Morgan
Published 2016-01-01