Recapitulating muscle disease phenotypes with myotonic dystrophy 1 induced pluripotent stem cells: a tool for disease modeling and drug discovery

by Ricardo Mondragon-Gonzalez, Rita C. R. Perlingeiro
Published 2018-07-01

Generation of skeletal myogenic progenitors from human pluripotent stem cells using non-viral delivery of minicircle DNA

by Jaemin Kim, Vanessa K.P. Oliveira, Ami Yamamoto, Rita C.R. Perlingeiro
Published 2017-08-01

Transplantation studies reveal internuclear transfer of toxic RNA in engrafted muscles of myotonic dystrophy 1 miceResearch in context

by Ricardo Mondragon-Gonzalez, Karim Azzag, Sridhar Selvaraj, Ami Yamamoto, Rita C.R. Perlingeiro
Published 2019-09-01

Pluripotent stem cell-derived skeletal muscle fibers preferentially express myosin heavy-chain isoforms associated with slow and oxidative muscles

by Tania Incitti, Alessandro Magli, Asher Jenkins, Karena Lin, Ami Yamamoto, Rita C. R. Perlingeiro
Published 2020-06-01

Chromatin accessibility profiling identifies evolutionary conserved loci in activated human satellite cells

by Lisa S. Chow, Darko Bosnakovski, Douglas G. Mashek, Michael Kyba, Rita C.R. Perlingeiro, Alessandro Magli
Published 2021-08-01

Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors

by Jaemin Kim, Alessandro Magli, Sunny S.K. Chan, Vanessa K.P. Oliveira, Jianbo Wu, Radbod Darabi, Michael Kyba, Rita C.R. Perlingeiro
Published 2017-07-01

Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology

by Nan Zhang, Julen Mendieta-Esteban, Alessandro Magli, Karin C. Lilja, Rita C. R. Perlingeiro, Marc A. Marti-Renom, Aristotelis Tsirigos, Brian David Dynlacht
Published 2020-12-01

Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification

by Alessandro Magli, June Baik, Pruthvi Pota, Carolina Ortiz Cordero, Il-Youp Kwak, Daniel J. Garry, Paul E. Love, Brian D. Dynlacht, Rita C. R. Perlingeiro
Published 2019-05-01

Efficient engraftment of pluripotent stem cell-derived myogenic progenitors in a novel immunodeficient mouse model of limb girdle muscular dystrophy 2I

by Karim Azzag, Carolina Ortiz-Cordero, Nelio A. J. Oliveira, Alessandro Magli, Sridhar Selvaraj, Sudheer Tungtur, Weston Upchurch, Paul A. Iaizzo, Qi Long Lu, Rita C. R. Perlingeiro
Published 2020-04-01

Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2

by June Baik, Alessandro Magli, Naoyuki Tahara, Scott A. Swanson, Naoko Koyano-Nakagawa, Luciene Borges, Ron Stewart, Daniel J. Garry, Yasuhiko Kawakami, James A. Thomson, Rita C. R. Perlingeiro
Published 2016-10-01

PAX7 Targets, CD54, Integrin α9β1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors

by Alessandro Magli, Tania Incitti, James Kiley, Scott A. Swanson, Radbod Darabi, Fabrizio Rinaldi, Sridhar Selvaraj, Ami Yamamoto, Jakub Tolar, Ce Yuan, Ron Stewart, James A. Thomson, Rita C.R. Perlingeiro
Published 2017-06-01

A universal gene correction approach for FKRP-associated dystroglycanopathies to enable autologous cell therapy

by Neha R. Dhoke, Hyunkee Kim, Sridhar Selvaraj, Karim Azzag, Haowen Zhou, Nelio A.J. Oliveira, Sudheer Tungtur, Carolina Ortiz-Cordero, James Kiley, Qi Long Lu, Anne G. Bang, Rita C.R. Perlingeiro
Published 2021-07-01

Dominant Lethal Pathologies in Male Mice Engineered to Contain an X-Linked DUX4 Transgene

by Abhijit Dandapat, Darko Bosnakovski, Lynn M. Hartweck, Robert W. Arpke, Kristen A. Baltgalvis, Derek Vang, June Baik, Radbod Darabi, Rita C.R. Perlingeiro, F. Kent Hamra, Kalpna Gupta, Dawn A. Lowe, Michael Kyba
Published 2014-09-01

Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm.

by Alessandro Magli, June Baik, Lauren J Mills, Il-Youp Kwak, Bridget S Dillon, Ricardo Mondragon Gonzalez, David A Stafford, Scott A Swanson, Ron Stewart, James A Thomson, Daniel J Garry, Brian D Dynlacht, Rita C R Perlingeiro
Published 2019-02-01

Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability

by Guadalupe Elizabeth Jimenez-Gutierrez, Ricardo Mondragon-Gonzalez, Luz Adriana Soto-Ponce, Wendy Lilián Gómez-Monsiváis, Ian García-Aguirre, Ruth Abigail Pacheco-Rivera, Rocío Suárez-Sánchez, Andrea Brancaccio, Jonathan Javier Magaña, Rita C.R. Perlingeiro, Bulmaro Cisneros
Published 2020-07-01

Myogenic Cell Transplantation in Genetic and Acquired Diseases of Skeletal Muscle

by Olivier Boyer, Gillian Butler-Browne, Hector Chinoy, Hector Chinoy, Giulio Cossu, Giulio Cossu, Giulio Cossu, Francesco Galli, James B. Lilleker, James B. Lilleker, Alessandro Magli, Vincent Mouly, Rita C. R. Perlingeiro, Stefano C. Previtali, Maurilio Sampaolesi, Maurilio Sampaolesi, Hubert Smeets, Hubert Smeets, Hubert Smeets, Verena Schoewel-Wolf, Simone Spuler, Yvan Torrente, Florence Van Tienen, Florence Van Tienen, Study Group, H. Aldearee, A. Bisson, L. Bragg, V. Bridoux, R. Duelen, A. Farini, E. Gazzero, N. Giarratana, C. Giverne, L. Meggiolaro, E. Negroni, E. Porrello, R. Tonlorenzi, C. Villa, L. Yedigaryan, A. Zamboni
Published 2021-08-01