Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding

by Tristan A Bell, Tania A Baker, Robert T Sauer
Published 2019-06-01

The Non-dominant AAA+ Ring in the ClpAP Protease Functions as an Anti-stalling Motor to Accelerate Protein Unfolding and Translocation

by Hema Chandra Kotamarthi, Robert T. Sauer, Tania A. Baker
Published 2020-02-01

Dissection of Axial-Pore Loop Function during Unfolding and Translocation by a AAA+ Proteolytic Machine

by Ohad Iosefson, Adrian O. Olivares, Tania A. Baker, Robert T. Sauer
Published 2015-08-01

Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates

by Xue Fei, Tristan A Bell, Sarah R Barkow, Tania A Baker, Robert T Sauer
Published 2020-10-01

ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP

by Sora Kim, Kristin L Zuromski, Tristan A Bell, Robert T Sauer, Tania A Baker
Published 2020-12-01

Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate

by Xue Fei, Tristan A Bell, Simon Jenni, Benjamin M Stinson, Tania A Baker, Stephen C Harrison, Robert T Sauer
Published 2020-02-01

Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

by Katherine Amberg-Johnson, Sanjay B Hari, Suresh M Ganesan, Hernan A Lorenzi, Robert T Sauer, Jacquin C Niles, Ellen Yeh
Published 2017-08-01

A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites.

by Yong Tang, Thomas R Meister, Marta Walczak, Michael J Pulkoski-Gross, Sanjay B Hari, Robert T Sauer, Katherine Amberg-Johnson, Ellen Yeh
Published 2019-02-01

Identifying determinants of folding and activity for a protein of unknown structure

by Bowie, James Ulrich
Published 2005

DegP related proteases in Escherichia coli and carboxyl-terminal tagging of proteins for degradation

by Waller, Patrick Robert Henson
Published 2008

Control of HslUV protease function by nucleotide binding and hydrolysis

by Yakamavich, Joseph Andrew
Published 2008

Mutagenic effects on protein folding and stability

by Anderson, Thomas Anthony, 1973-
Published 2005

Specificity and regulation of substrate degradation for a AAA+ protease

by Farrell, Christopher Mark
Published 2007

β-sheet interactions with DNA revealed by the arc repressor-operator complex

by Raumann, Brigitte Elke
Published 2006

ClpX interactions with ClpP, SspB, protein substrate and nucleotide

by Hersch, Greg Louis
Published 2008

Regulation of ClpP : role of substrate gating and activation by ClpX

by Lee, Mary Elizabeth, Ph. D. Massachusetts Institute of Technology
Published 2010

The role of hydrophobic core in protein folding

by Lim, Wendel Alan
Published 2005

Substrate denaturation and translocation by a proteolytic machine

by Kenniston, Jon Anders
Published 2006

Mechanisms of substrate recognition by the AAA+ protease HslUV

by Sundar, Shankar
Published 2011

The role of the N domain in substrate binding, oligomerization, and allosteric regulation of the AAA+ Lon protease

by Wohlever, Matthew L
Published 2013