Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

by Alex Graudenzi, Davide Maspero, Fabrizio Angaroni, Rocco Piazza, Daniele Ramazzotti
Published 2021-02-01

An Imatinib–non‐responsive patient with an ABL Leu387Trp mutation achieves cytogenetic and molecular response under bosutinib: Case report and biological characterization

by Ilaria Crespiatico, Elisa Bossi, Filippo Brioschi, Rocco Piazza, Luca Mologni, Carlo Gambacorti‐Passerini
Published 2020-01-01

An Optimal Control Framework for the Automated Design of Personalized Cancer Treatments

by Fabrizio Angaroni, Alex Graudenzi, Alex Graudenzi, Marco Rossignolo, Marco Rossignolo, Davide Maspero, Davide Maspero, Davide Maspero, Tommaso Calarco, Rocco Piazza, Rocco Piazza, Simone Montangero, Simone Montangero, Marco Antoniotti, Marco Antoniotti
Published 2020-05-01

<i>HIF1A:</i> A Putative Modifier of Hemochromatosis

by Sara Pelucchi, Giulia Ravasi, Cristina Arosio, Mario Mauri, Rocco Piazza, Raffaella Mariani, Alberto Piperno
Published 2021-01-01

Mitochondrial Hyperactivation and Enhanced ROS Production are Involved in Toxicity Induced by Oncogenic Kinases Over-Signaling

by Monica Ceccon, Mario Mauri, Luca Massimino, Giovanni Giudici, Rocco Piazza, Carlo Gambacorti-Passerini, Luca Mologni
Published 2018-12-01

The Giant HECT E3 Ubiquitin Ligase HERC1 Is Aberrantly Expressed in Myeloid Related Disorders and It Is a Novel BCR-ABL1 Binding Partner

by Muhammad Shahzad Ali, Cristina Panuzzo, Chiara Calabrese, Alessandro Maglione, Rocco Piazza, Daniela Cilloni, Giuseppe Saglio, Barbara Pergolizzi, Enrico Bracco
Published 2021-01-01

Germ-Line TP53 Mutation in an Adolescent With CMML/Atypical CML and Familiar Cancer Predisposition

by Silvia Nucera, Grazia Fazio, Rocco Piazza, Silvia Rigamonti, Diletta Fontana, Carlo Gambacorti Passerini, Silvia Maitz, Attilio Rovelli, Andrea Biondi, Giovauni Cazzaniga, Adriana Balduzzi
Published 2020-10-01

CEQer: a graphical tool for copy number and allelic imbalance detection from whole-exome sequencing data.

by Rocco Piazza, Vera Magistroni, Alessandra Pirola, Sara Redaelli, Roberta Spinelli, Serena Redaelli, Marta Galbiati, Simona Valletta, Giovanni Giudici, Giovanni Cazzaniga, Carlo Gambacorti-Passerini
Published 2013-01-01

Concomitant BCORL1 and BRAF Mutations in Vemurafenib-Resistant Melanoma Cells

by Luca Mologni, Mariantonia Costanza, Geeta Geeta Sharma, Michela Viltadi, Luca Massimino, Stefania Citterio, Stefania Purgante, Hima Raman, Alessandra Pirola, Massimo Zucchetti, Rocco Piazza, Carlo Gambacorti-Passerini
Published 2018-05-01

ERG deregulation induces PIM1 over-expression and aneuploidy in prostate epithelial cells.

by Vera Magistroni, Luca Mologni, Stefano Sanselicio, James Frances Reid, Sara Redaelli, Rocco Piazza, Michela Viltadi, Giorgio Bovo, Guido Strada, Marco Grasso, Manuela Gariboldi, Carlo Gambacorti-Passerini
Published 2011-01-01

Epigenetic Silencing of the Proapoptotic Gene BIM in Anaplastic Large Cell Lymphoma through an MeCP2/SIN3a Deacetylating Complex

by Rocco Piazza, Vera Magistroni, Angela Mogavero, Federica Andreoni, Chiara Ambrogio, Roberto Chiarle, Luca Mologni, Petra S Bachmann, Richard B Lock, Paola Collini, Giuseppe Pelosi, Carlo Gambacorti-Passerini
Published 2013-05-01

Human Chromosome 18 and Acrocentrics: A Dangerous Liaison

by Nicoletta Villa, Serena Redaelli, Elena Sala, Donatella Conconi, Lorenza Romitti, Emanuela Manfredini, Francesca Crosti, Gaia Roversi, Marialuisa Lavitrano, Ornella Rodeschini, Maria Paola Recalcati, Rocco Piazza, Leda Dalprà, Paola Riva, Angela Bentivegna
Published 2021-05-01

SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome

by Federica Banfi, Alicia Rubio, Mattia Zaghi, Luca Massimino, Giulia Fagnocchi, Edoardo Bellini, Mirko Luoni, Cinzia Cancellieri, Anna Bagliani, Chiara Di Resta, Camilla Maffezzini, Angelo Ianielli, Maurizio Ferrari, Rocco Piazza, Luca Mologni, Vania Broccoli, Alessandro Sessa
Published 2021-06-01

IκBα targeting promotes oxidative stress-dependent cell death

by Giovanna Carrà, Giuseppe Ermondi, Chiara Riganti, Luisella Righi, Giulia Caron, Alessio Menga, Enrica Capelletto, Beatrice Maffeo, Marcello Francesco Lingua, Federica Fusella, Marco Volante, Riccardo Taulli, Angelo Guerrasio, Silvia Novello, Mara Brancaccio, Rocco Piazza, Alessandro Morotti
Published 2021-04-01

Synergistic Drug Combinations Prevent Resistance in ALK+ Anaplastic Large Cell Lymphoma

by Giulia Arosio, Geeta G. Sharma, Matteo Villa, Mario Mauri, Ilaria Crespiatico, Diletta Fontana, Chiara Manfroni, Cristina Mastini, Marina Zappa, Vera Magistroni, Monica Ceccon, Sara Redaelli, Luca Massimino, Anna Garbin, Federica Lovisa, Lara Mussolin, Rocco Piazza, Carlo Gambacorti-Passerini, Luca Mologni
Published 2021-09-01

SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub

by Rocco Piazza, Vera Magistroni, Sara Redaelli, Mario Mauri, Luca Massimino, Alessandro Sessa, Marco Peronaci, Maciej Lalowski, Rabah Soliymani, Caterina Mezzatesta, Alessandra Pirola, Federica Banfi, Alicia Rubio, Delphine Rea, Fabio Stagno, Emilio Usala, Bruno Martino, Leonardo Campiotti, Michele Merli, Francesco Passamonti, Francesco Onida, Alessandro Morotti, Francesca Pavesi, Marco Bregni, Vania Broccoli, Marc Baumann, Carlo Gambacorti-Passerini
Published 2018-06-01

Case Report: Hypomorphic Function and Somatic Reversion in DOCK8 Deficiency in One Patient With Two Novel Variants and Sclerosing Cholangitis

by Francesco Saettini, Grazia Fazio, Daniele Moratto, Marta Galbiati, Nicola Zucchini, Davide Ippolito, Marco Emilio Dinelli, Luisa Imberti, Mario Mauri, Maria Luisa Melzi, Sonia Bonanomi, Alessio Gerussi, Alessio Gerussi, Marinella Pinelli, Chiara Barisani, Cristina Bugarin, Marco Chiarini, Mauro Giacomelli, Rocco Piazza, Giovanni Cazzaniga, Giovanni Cazzaniga, Pietro Invernizzi, Pietro Invernizzi, Silvia Clara Giliani, Raffaele Badolato, Andrea Biondi, Andrea Biondi
Published 2021-04-01

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

by Diletta Fontana, Mario Mauri, Rossella Renso, Mattia Docci, Ilaria Crespiatico, Lisa M. Røst, Mi Jang, Antonio Niro, Deborah D’Aliberti, Luca Massimino, Mayla Bertagna, Giovanni Zambrotta, Mario Bossi, Stefania Citterio, Barbara Crescenzi, Francesca Fanelli, Valeria Cassina, Roberta Corti, Domenico Salerno, Luca Nardo, Clizia Chinello, Francesco Mantegazza, Cristina Mecucci, Fulvio Magni, Guido Cavaletti, Per Bruheim, Delphine Rea, Steen Larsen, Carlo Gambacorti-Passerini, Rocco Piazza
Published 2020-11-01

Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia

by Diletta Fontana, Daniele Ramazzotti, Andrea Aroldi, Sara Redaelli, Vera Magistroni, Alessandra Pirola, Antonio Niro, Luca Massimino, Cristina Mastini, Virginia Brambilla, Silvia Bombelli, Silvia Bungaro, Alessandro Morotti, Delphine Rea, Fabio Stagno, Bruno Martino, Leonardo Campiotti, Giovanni Caocci, Emilio Usala, Michele Merli, Francesco Onida, Marco Bregni, Elena Maria Elli, Monica Fumagalli, Fabio Ciceri, Roberto A. Perego, Fabio Pagni, Luca Mologni, Rocco Piazza, Carlo Gambacorti-Passerini
Published 2020-12-01