Molecular structures of the human Slo1 K+ channel in complex with β4

by Xiao Tao, Roderick MacKinnon
Published 2019-12-01

Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology

by Xiao Tao, Roderick MacKinnon
Published 2019-11-01

Structure of the CLC-1 chloride channel from Homo sapiens

by Eunyong Park, Roderick MacKinnon
Published 2018-05-01

Regulation of Eag1 gating by its intracellular domains

by Jonathan R Whicher, Roderick MacKinnon
Published 2019-09-01

Piezo’s membrane footprint and its contribution to mechanosensitivity

by Christoph A Haselwandter, Roderick MacKinnon
Published 2018-11-01

Molecular basis of signaling specificity between GIRK channels and GPCRs

by Kouki K Touhara, Roderick MacKinnon
Published 2018-12-01

Structure-based membrane dome mechanism for Piezo mechanosensitivity

by Yusong R Guo, Roderick MacKinnon
Published 2017-12-01

Structural and thermodynamic properties of selective ion binding in a K+ channel.

by Steve W Lockless, Ming Zhou, Roderick MacKinnon
Published 2007-05-01

The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers

by Kouki K Touhara, Weiwei Wang, Roderick MacKinnon
Published 2016-04-01

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

by Weiwei Wang, Matthew R Whorton, Roderick MacKinnon
Published 2014-07-01

Molecular structure of human KATP in complex with ATP and ADP

by Kenneth Pak Kin Lee, Jue Chen, Roderick MacKinnon
Published 2017-12-01

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

by Anirban Banerjee, Alice Lee, Ernest Campbell, Roderick MacKinnon
Published 2013-05-01

Phosphatidic acid modulation of Kv channel voltage sensor function

by Richard K Hite, Joel A Butterwick, Roderick MacKinnon
Published 2014-10-01

Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels.

by Seok-Yong Lee, Anirban Banerjee, Anirban Banerjee, Roderick MacKinnon
Published 2009-03-01

Cryo-EM analysis of PIP2 regulation in mammalian GIRK channels

by Yiming Niu, Xiao Tao, Kouki K Touhara, Roderick MacKinnon
Published 2020-08-01

Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells

by Josefina Inés del Mármol, Kouki K Touhara, Gist Croft, Roderick MacKinnon
Published 2018-08-01

Cooperative regulation by G proteins and Na+ of neuronal GIRK2 K+ channels

by Weiwei Wang, Kouki K Touhara, Keiko Weir, Bruce P Bean, Roderick MacKinnon
Published 2016-04-01

The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier

by Stephen G Brohawn, Weiwei Wang, Annie Handler, Ernest B Campbell, Jürgen R Schwarz, Roderick MacKinnon
Published 2019-11-01

Analysis of the mechanosensor channel functionality of TACAN

by Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon
Published 2021-08-01