Lentiviral vectors to probe and manipulate the Wnt signaling pathway.

by Christophe Fuerer, Roel Nusse
Published 2010-02-01

Mutants in the mouse NuRD/Mi2 component P66alpha are embryonic lethal.

by Susan Marino, Roel Nusse
Published 2007-06-01

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.

by Amanda J Mikels, Roel Nusse
Published 2006-04-01

In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus.

by Si Hui Tan, Roel Nusse
Published 2017-01-01

Live Imaging Reveals that the First Division of Differentiating Human Embryonic Stem Cells Often Yields Asymmetric Fates

by Katharine Brown, Kyle M. Loh, Roel Nusse
Published 2017-10-01

Pathogenesis of listeria-infected Drosophila wntD mutants is associated with elevated levels of the novel immunity gene edin.

by Michael D Gordon, Janelle S Ayres, David S Schneider, Roel Nusse
Published 2008-07-01

Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments.

by Zach Klapholz-Brown, Graham G Walmsley, Ysbrand M Nusse, Roel Nusse, Patrick O Brown
Published 2007-09-01

A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration.

by Mark A McElwain, Dennis C Ko, Michael D Gordon, Henrik Fyrst, Julie D Saba, Roel Nusse
Published 2011-01-01

Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells

by John P Russell, Xinhong Lim, Alice Santambrogio, Val Yianni, Yasmine Kemkem, Bruce Wang, Matthew Fish, Scott Haston, Anaëlle Grabek, Shirleen Hallang, Emily J Lodge, Amanda L Patist, Andreas Schedl, Patrice Mollard, Roel Nusse, Cynthia L Andoniadou
Published 2021-01-01

In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration

by Yuval Rinkevich, Daniel T. Montoro, Humberto Contreras-Trujillo, Orit Harari-Steinberg, Aaron M. Newman, Jonathan M. Tsai, Xinhong Lim, Renee Van-Amerongen, Angela Bowman, Michael Januszyk, Oren Pleniceanu, Roel Nusse, Michael T. Longaker, Irving L. Weissman, Benjamin Dekel
Published 2014-05-01

Liposomal packaging generates Wnt protein with in vivo biological activity.

by Nathan T Morrell, Philipp Leucht, Ludan Zhao, Jae-Beom Kim, Derk ten Berge, Karthik Ponnusamy, A Lyonel Carre, Henryk Dudek, Marie Zachlederova, Michael McElhaney, Shirley Brunton, Janet Gunzner, Marinella Callow, Paul Polakis, Mike Costa, Xiaoyan M Zhang, Jill A Helms, Roel Nusse
Published 2008-08-01

Honey bee Royalactin unlocks conserved pluripotency pathway in mammals

by Derrick C. Wan, Stefanie L. Morgan, Andrew L. Spencley, Natasha Mariano, Erin Y. Chang, Gautam Shankar, Yunhai Luo, Ted H. Li, Dana Huh, Star K. Huynh, Jasmine M. Garcia, Cole M. Dovey, Jennifer Lumb, Ling Liu, Katharine V. Brown, Abel Bermudez, Richard Luong, Hong Zeng, Victoria L. Mascetti, Sharon J. Pitteri, Jordon Wang, Hua Tu, Marco Quarta, Vittorio Sebastiano, Roel Nusse, Thomas A. Rando, Jan E. Carette, J. Fernando Bazan, Kevin C. Wang
Published 2018-12-01