Restoring KLF5 in Esophageal Squamous Cell Cancer Cells Activates the JNK Pathway Leading to Apoptosis and Reduced Cell Survival

by Rohinton S Tarapore, Yizeng Yang, Jonathan P Katz
Published 2013-05-01

BMI1 polycomb group protein acts as a master switch for growth and death of tumor cells: regulates TCF4-transcriptional factor-induced BCL2 signaling.

by Hifzur Rahman Siddique, Aijaz Parray, Rohinton S Tarapore, Lei Wang, Hasan Mukhtar, R Jeffery Karnes, Yibin Deng, Badrinath R Konety, Mohammad Saleem
Published 2013-01-01

Correction: Hu, W., et al. Targeting Dopamine Receptor D2 by Imipridone Suppresses Uterine Serous Cancer Malignant Phenotype. <i>Cancers</i> 2020, <i>12</i>, 2436

by Wen Hu, Li Zhang, Sammy Ferri-Borgogno, Suet-Ying Kwan, Kelsey E. Lewis, Han T. Cun, Tsz-Lun Yeung, Pamela T. Soliman, Rohinton S. Tarapore, Joshua E. Allen, Xinyuan Guan, Karen H. Lu, Samuel C. Mok, Chi-Lam Au-Yeung
Published 2021-02-01

Targeting Dopamine Receptor D2 by Imipridone Suppresses Uterine Serous Cancer Malignant Phenotype

by Wen Hu, Li Zhang, Sammy Ferri-Borgogno, Suet-Ying Kwan, Kelsey E. Lewis, Han T. Cun, Tsz-Lun Yeung, Pamela T. Soliman, Rohinton S. Tarapore, Joshua E. Allen, Xinyuan Guan, Karen H. Lu, Samuel C. Mok, Chi-Lam Au-Yeung
Published 2020-08-01

ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

by Varun Vijay Prabhu, Sara Morrow, Abed Rahman Kawakibi, Lanlan Zhou, Marie Ralff, Jocelyn Ray, Aakash Jhaveri, Isacco Ferrarini, Young Lee, Cassandra Parker, Yiqun Zhang, Robyn Borsuk, Wen-I Chang, Joshua N. Honeyman, Fabio Tavora, Benedito Carneiro, Alexander Raufi, Kelsey Huntington, Lindsey Carlsen, Anna Louie, Howard Safran, Attila A. Seyhan, Rohinton S. Tarapore, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, Wafik S. El-Deiry
Published 2020-12-01

Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

by Mark N. Stein, Jyoti Malhotra, Rohinton S. Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert D. Aiken, Tina Mayer, Bruce G. Haffty, Jenna H. Newman, Salvatore M. Aspromonte, Praveen K. Bommareddy, Ricardo Estupinian, Charles B. Chesson, Evita T. Sadimin, Shengguo Li, Daniel J. Medina, Tracie Saunders, Melissa Frankel, Aparna Kareddula, Sherrie Damare, Elayne Wesolowsky, Christian Gabel, Wafik S. El-Deiry, Varun V. Prabhu, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Joseph R. Bertino, Steven K. Libutti, Janice M. Mehnert, Andrew Zloza
Published 2019-05-01