Cigarette Smoke Induces the Risk of Metabolic Bone Diseases: Transforming Growth Factor Beta Signaling Impairment via Dysfunctional Primary Cilia Affects Migration, Proliferation,...

by Romina H. Aspera-Werz, Tao Chen, Sabrina Ehnert, Sheng Zhu, Theresa Fröhlich, Andreas K. Nussler
Published 2019-06-01

Primary Human Chondrocytes Affected by Cigarette Smoke—Therapeutic Challenges

by Tao Chen, Sabrina Ehnert, Gauri Tendulkar, Sheng Zhu, Christian Arnscheidt, Romina H. Aspera-Werz, Andreas K. Nussler
Published 2020-03-01

Translational Insights into Extremely Low Frequency Pulsed Electromagnetic Fields (ELF-PEMFs) for Bone Regeneration after Trauma and Orthopedic Surgery

by Sabrina Ehnert, Steffen Schröter, Romina H. Aspera-Werz, Wiebke Eisler, Karsten Falldorf, Michael Ronniger, Andreas K. Nussler
Published 2019-11-01

From the Clinical Problem to the Basic Research—Co-Culture Models of Osteoblasts and Osteoclasts

by Sheng Zhu, Sabrina Ehnert, Marc Rouß, Victor Häussling, Romina H. Aspera-Werz, Tao Chen, Andreas K. Nussler
Published 2018-08-01

Update on Novel Non-Operative Treatment for Osteoarthritis: Current Status and Future Trends

by Tao Chen, Tao Chen, Weidong Weng, Yang Liu, Romina H. Aspera-Werz, Andreas K Nüssler, Jianzhong Xu
Published 2021-09-01

Bisphosphonates Reduce Smoking-Induced Osteoporotic-Like Alterations by Regulating RANKL/OPG in an Osteoblast and Osteoclast Co-Culture Model

by Sheng Zhu, Victor Häussling, Romina H. Aspera-Werz, Tao Chen, Bianca Braun, Weidong Weng, Tina Histing, Andreas K. Nussler
Published 2021-12-01

Donor Site Location Is Critical for Proliferation, Stem Cell Capacity, and Osteogenic Differentiation of Adipose Mesenchymal Stem/Stromal Cells: Implications for Bone Tissue Engine...

by Marie K. Reumann, Caren Linnemann, Romina H. Aspera-Werz, Sigrid Arnold, Manuel Held, Claudine Seeliger, Andreas K. Nussler, Sabrina Ehnert
Published 2018-06-01

Feasibility of Cell Lines for In Vitro Co-Cultures Models for Bone Metabolism

by Sabrina Ehnert, Caren Linnemann, Romina H. Aspera-Werz, Victor Häussling, Bianca Braun, Weidong Weng, Sheng Zhu, Kristian C. Ngamsri, Andreas Nussler
Published 2020-09-01

Smoking Dependent Alterations in Bone Formation and Inflammation Represent Major Risk Factors for Complications Following Total Joint Arthroplasty

by Sabrina Ehnert, Romina H. Aspera-Werz, Christoph Ihle, Markus Trost, Barbara Zirn, Ingo Flesch, Steffen Schröter, Borna Relja, Andreas K. Nussler
Published 2019-03-01

Nicotine and Cotinine Inhibit Catalase and Glutathione Reductase Activity Contributing to the Impaired Osteogenesis of SCP-1 Cells Exposed to Cigarette Smoke

by Romina H. Aspera-Werz, Sabrina Ehnert, Daniel Heid, Sheng Zhu, Tao Chen, Bianca Braun, Vrinda Sreekumar, Christian Arnscheidt, Andreas K. Nussler
Published 2018-01-01

Exposure to 16 Hz Pulsed Electromagnetic Fields Protect the Structural Integrity of Primary Cilia and Associated TGF-β Signaling in Osteoprogenitor Cells Harmed by Cigarette Smoke

by Yangmengfan Chen, Romina H. Aspera-Werz, Maximilian M. Menger, Karsten Falldorf, Michael Ronniger, Christina Stacke, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Published 2021-06-01

Material-Dependent Formation and Degradation of Bone Matrix—Comparison of Two Cryogels

by Weidong Weng, Victor Häussling, Romina H. Aspera-Werz, Fabian Springer, Helen Rinderknecht, Bianca Braun, Markus A. Küper, Andreas K. Nussler, Sabrina Ehnert
Published 2020-06-01

Hepatic Osteodystrophy—Molecular Mechanisms Proposed to Favor Its Development

by Sabrina Ehnert, Romina H. Aspera-Werz, Marc Ruoß, Steven Dooley, Jan G. Hengstler, Silvio Nadalin, Borna Relja, Andreas Badke, Andreas K. Nussler
Published 2019-05-01

3D Environment Is Required in Vitro to Demonstrate Altered Bone Metabolism Characteristic for Type 2 Diabetics

by Victor Häussling, Romina H Aspera-Werz, Helen Rinderknecht, Fabian Springer, Christian Arnscheidt, Maximilian M Menger, Tina Histing, Andreas K Nussler, Sabrina Ehnert
Published 2021-03-01

Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase

by Sabrina Ehnert, Caren Linnemann, Romina H. Aspera-Werz, Daria Bykova, Sara Biermann, Leonie Fecht, Peter M. De Zwart, Andreas K. Nussler, Fabian Stuby
Published 2018-07-01

A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation

by Weidong Weng, Filippo Zanetti, David Bovard, Bianca Braun, Sabrina Ehnert, Tatiana Uynuk-Ool, Tina Histing, Julia Hoeng, Andreas K. Nussler, Romina H. Aspera-Werz
Published 2021-09-01