Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes

by Jian-Jung Pan, Jose O. Solbiati, Gurusankar Ramamoorthy, Brandan S. Hillerich, Ronald D. Seidel, John E. Cronan, Steven C. Almo, C. Dale Poulter
Published 2015-04-01

Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.

by Sarah C Garrett-Thomson, Aldo Massimi, Elena V Fedorov, Jeffrey B Bonanno, Lisa Scandiuzzi, Brandan Hillerich, Ronald D Seidel, James D Love, Scott J Garforth, Chandan Guha, Steven C Almo
Published 2020-01-01

Peptide-HLA-based immunotherapeutics platforms for direct modulation of antigen-specific T cells

by Ronald D. Seidel, Zohra Merazga, Dharma Raj Thapa, Jonathan Soriano, Emily Spaulding, Ahmet S. Vakkasoglu, Paige Ruthardt, Wynona Bautista, Steven N. Quayle, Peter A. Kiener, Simon Low, John F. Ross, Saso Cemerski, Anish Suri, Steven C. Almo, Rodolfo J. Chaparro
Published 2021-09-01

Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.

by Susan T Mashiyama, M Merced Malabanan, Eyal Akiva, Rahul Bhosle, Megan C Branch, Brandan Hillerich, Kevin Jagessar, Jungwook Kim, Yury Patskovsky, Ronald D Seidel, Mark Stead, Rafael Toro, Matthew W Vetting, Steven C Almo, Richard N Armstrong, Patricia C Babbitt
Published 2014-04-01

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

by Suwen Zhao, Ayano Sakai, Xinshuai Zhang, Matthew W Vetting, Ritesh Kumar, Brandan Hillerich, Brian San Francisco, Jose Solbiati, Adam Steves, Shoshana Brown, Eyal Akiva, Alan Barber, Ronald D Seidel, Patricia C Babbitt, Steven C Almo, John A Gerlt, Matthew P Jacobson
Published 2014-06-01