Epigenetic-genetic chromosome dosage approach for fetal trisomy 21 detection using an autosomal genetic reference marker.

by Yu K Tong, Rossa W K Chiu, Ranjit Akolekar, Tak Y Leung, Tze K Lau, Kypros H Nicolaides, Y M Dennis Lo
Published 2010-01-01

Maternal plasma fetal DNA fractions in pregnancies with low and high risks for fetal chromosomal aneuploidies.

by Irena Hudecova, Daljit Sahota, Macy M S Heung, Yongjie Jin, Wing S Lee, Tak Y Leung, Yuk Ming Dennis Lo, Rossa W K Chiu
Published 2014-01-01

Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA.

by Gary J W Liao, K C Allen Chan, Peiyong Jiang, Hao Sun, Tak Y Leung, Rossa W K Chiu, Y M Dennis Lo
Published 2012-01-01

Tracing SARS-Coronavirus Variant with Large Genomic Deletion

by Rossa W.K. Chiu, Stephen S.C. Chim, Yu-kwan Tong, Kitty S.C. Fung, Paul K.S. Chan, Guo-ping Zhao, Y.M. Dennis Lo
Published 2005-01-01

Placenta-derived fetal specific mRNA is more readily detectable in maternal plasma than in whole blood.

by Macy M S Heung, Shengnan Jin, Nancy B Y Tsui, Chunming Ding, Tak Y Leung, Tze K Lau, Rossa W K Chiu, Y M Dennis Lo
Published 2009-06-01

Methy-Pipe: an integrated bioinformatics pipeline for whole genome bisulfite sequencing data analysis.

by Peiyong Jiang, Kun Sun, Fiona M F Lun, Andy M Guo, Huating Wang, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo, Hao Sun
Published 2014-01-01

High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing.

by Nancy B Y Tsui, Peiyong Jiang, Katherine C K Chow, Xiaoxi Su, Tak Y Leung, Hao Sun, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo
Published 2012-01-01

SFRS7-mediated splicing of tau exon 10 is directly regulated by STOX1A in glial cells.

by Daan van Abel, Dennis R Hölzel, Shushant Jain, Fiona M F Lun, Yama W L Zheng, Eric Z Chen, Hao Sun, Rossa W K Chiu, Y M Dennis Lo, Marie van Dijk, Cees B M Oudejans
Published 2011-01-01

Noninvasive prenatal molecular karyotyping from maternal plasma.

by Stephanie C Y Yu, Peiyong Jiang, Kwong W Choy, Kwan Chee Allen Chan, Hye-Sung Won, Wing C Leung, Elizabeth T Lau, Mary H Y Tang, Tak Y Leung, Yuk Ming Dennis Lo, Rossa W K Chiu
Published 2013-01-01

Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome.

by Dana W Y Tsui, Y M Doris Lam, Wing S Lee, Tak Y Leung, Tze K Lau, Elizabeth T Lau, Mary H Y Tang, Ranjit Akolekar, Kypros H Nicolaides, Rossa W K Chiu, Y M Dennis Lo, Stephen S C Chim
Published 2010-01-01

Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

by W. K. Jacky Lam, Peiyong Jiang, K. C. Allen Chan, Wenlei Peng, Huimin Shang, Macy M. S. Heung, Suk Hang Cheng, Haiqiang Zhang, O. Y. Olivia Tse, Radha Raghupathy, Brigette B. Y. Ma, Edwin P. Hui, Anthony T. C. Chan, John K. S. Woo, Rossa W. K. Chiu, Y. M. Dennis Lo
Published 2019-07-01

Dissection of <i>PIK3CA</i> Aberration for Cervical Adenocarcinoma Outcomes

by Tony K. H. Chung, Graeme Doran, Tak-Hong Cheung, So-Fan Yim, Mei-Yung Yu, Michael J. Worley, Kevin M. Elias, Aaron R. Thorner, Chandra Sekhar Pedamallu, Akinyemi I. Ojesina, Kei-Man Lau, Matthew D. Ducar, Raymond R. Y. Wong, Vivian W. Wang, Anwesha Nag, Bruce M. Wollison, Audrey Dalgarno, Jacqueline H. S. Lee, Suet-Ying Yeung, Lo Wong, Neil S. Horowitz, Michelle R. Davis, Shuk-On A. Leung, Yi Mu, Samuel C. Mok, Paul K. S. Chan, Michael S. Lawrence, Christopher P. Crum, Rossa W. K. Chiu, Ross S. Berkowitz, Yick-Fu Wong
Published 2021-06-01

Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing.

by Eric Z Chen, Rossa W K Chiu, Hao Sun, Ranjit Akolekar, K C Allen Chan, Tak Y Leung, Peiyong Jiang, Yama W L Zheng, Fiona M F Lun, Lisa Y S Chan, Yongjie Jin, Attie T J I Go, Elizabeth T Lau, William W K To, Wing C Leung, Rebecca Y K Tang, Sidney K C Au-Yeung, Helena Lam, Yu Y Kung, Xiuqing Zhang, John M G van Vugt, Ryoko Minekawa, Mary H Y Tang, Jun Wang, Jun Wang, Cees B M Oudejans, Tze K Lau, Kypros H Nicolaides, Y M Dennis Lo
Published 2011-01-01